The remarkable decline in the incidence of syphilis in the first half of the 20th century tempted many observers to share the view of Illingworth (1959) that it was a disappearing disease. Since 1957, however, there has been an unmistakable upward trend in many parts of the world (Stallworthy and Bourne, 1966; Walter and Israel, 1965), and many cases of florid congenital syphilis have been repo...

The diagnosis of occult staphylococcal infection of bone is often difficult. Two cases are presented that illustrate the use of the anti-alpha haemolysin titration. In the second case this test appears to have been of value as a guide to effective chemotherapy. Such cases are now infrequent and we publish these results in the hope that further knowledge of the efficiency of this test may be sou...

1. The most important challenge in diagnosis of celiac disease is not-performing the diagnostic tests in suspected persons. Because of multi-organ damage and multiple manifestations of disease, diagnosis of celiac disease may be delayed. It seems general physicians should be aware about uncommon presentations of disease and indications of celiac tests. 2. The second most important challenge is ...

Serologic reactions in leprosy infection have not been studied with as much interest as other aspects of the infection, for various reasons. Inability to cultivate the causative agent in vitro has made preparation of even relatively purc antigens difficult. Positive serologic tes ts are not characterized by an absolute specificity for leprosy, in part because no antigen. specific f~r the lepros...

Hepaxpert-I is an expert system that interprets the results of routine serologic tests for infection with hepatitis A or B virus. The tests measure antibody to the hepatitis A virus (anti-HAV), IgM antibody to the hepatitis A virus (IgM anti-HAV), hepatitis A virus (HAV) in the stool, hepatitis B surface antigen (HBsAg) and antibody (anti-HBs), antibody to hepatitis B core antigen (anti-HBc and...