PURPOSE The incidence of sensorineural hearing loss (SNHL) after treatment with combination of intensity-modulated radiation therapy (IMRT) and cisplatin-based chemotherapy in nasopharyngeal carcinoma (NPC) patients was evaluated, and relationships of SNHL with host factors, treatment-related factors, and radiation dosimetric parameters were investigated. METHODS Fifty-one NPC patients treate...

background hearing loss is the most common congenital disorder the incidence of which is further increased in the presence of risk factors for hearing loss among newborns admitted to the neonatal intensive care unit (nicu). the aim of this study was early diagnosis and intervention for hearing loss in newborns discharged from nicu. materials and methods this prospective cohort study was conduct...

Aim:Our study aims at evaluate auditory dysfunction in patients with diabetes mellitus aged above 50 years as compared to non-diabetic patient,it’s relationshipwith the duration of diabetes and HbA1c levels and to evaluatethe central auditory pathway involvement in diabetic patients by Brainstem Evoked response audiometry(BERA). Materials And Methods: A cross sectional, comparative clinical stu...

Although sensorineural hearing loss (SNHL) is known to compromise central auditory structure and function, the impact of milder forms of hearing loss on cellular neurophysiology remains mostly undefined. We induced conductive hearing loss (CHL) in developing gerbils, reared the animals for 8-13 d, and subsequently assessed the temporal features of auditory cortex layer 2/3 pyramidal neurons in ...

Verbal communication in noisy backgrounds is challenging. Understanding speech in background noise that fluctuates in intensity over time is particularly difficult for hearing-impaired listeners with a sensorineural hearing loss (SNHL). The reduction in fast-acting cochlear compression associated with SNHL exaggerates the perceived fluctuations in intensity in amplitude-modulated sounds. SNHL-i...

The major consequence of sensorineural hearing loss (SNHL) is communicative difficulty, especially with the addition of noise and/or reverberation. The purpose of this investigation was to compare two types of technologies that have been shown to improve the speech-perception performance of individuals with SNHL: directional microphones and frequency modulation (FM) systems. Forty-six adult sub...

CONCLUSIONS Congenital cytomegalovirus (CMV) infection is a major cause of bilateral and unilateral sensorineural hearing loss (SNHL) in children, accounting for 9.0% of SNHL cases. The diagnostic rate using combined genetic deafness test and CMV DNA detection test was determined to be 46.4% in bilateral profound SNHL. OBJECTIVES The present study investigated the prevalence of congenital CMV...

Background and Objectives Middle ear implants (MEI) have been reported to be an effective safe alternative for the treatment of sensorineural hearing loss (SNHL) conductive (CHL). This study aimed compare functional outcomes between SNHL CHL in terms audiological gains.Subjects Method The medical records 14 consecutive patients who underwent MEI surgeries from 2015 2019 by a single surgeon were...

Heimler syndrome (HS) is a rare recessive disorder characterized by sensorineural hearing loss (SNHL), amelogenesis imperfecta, nail abnormalities, and occasional or late-onset retinal pigmentation. We ascertained eight families affected by HS and, by using a whole-exome sequencing approach, identified biallelic mutations in PEX1 or PEX6 in six of them. Loss-of-function mutations in both genes ...

OBJECTIVE To review the role of routine hearing screening for sensorineural hearing loss (SNHL) in children with cystic fibrosis (CF) who have been on aminoglycoside therapy. DATA SOURCES PubMed, Cochrane, Scopus, and Ovid databases. REVIEW METHODS A systematic review of the literature was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyse...