نتایج جستجو برای: semicarbazones
تعداد نتایج: 186 فیلتر نتایج به سال:
It has long been recognized that many of the steroids, including the androgens, are excreted in urine in conjugation with other substances which render them not only more water-soluble but also neutralize their physiological activity to a great extent. In 1936 Cohen and Marrian (1) isolated estriol glucuronide, the conjugated form of estriol, from the urine of pregnant women and in 1936 Venning...
Cancer cells have a high iron requirement and many experimental studies, as well as clinical trials, have demonstrated that iron chelators are potential anti-cancer agents. The ligand, 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone (Bp4eT), demonstrates both potent anti-neoplastic and anti-retroviral properties. In this study, Bp4eT and its recently identified amidrazone and semicarbazone metabo...
Preliminary results are reported of antimicrobial assays conducted with chemically synthesized derivatives of patulin, a mycotoxin produced by several species of Penicillia and Aspergilli. Patulin (Fig. 1) has been shown to be an antibiotic1) and a carcinogen2); it is considered too toxic for humans or animals3) and is inhibitory to plants4). It is an a,R-unsaturated r-lactone with two conjugat...
Antiparasitics for the treatment of companion animals and livestock is one largest global market segments in animal health industry.Parasitic infections caused by endo- ectoparasites – latter also transmitting vector-borne diseases are among most significant worldwide, both humans.Most antiparasitic active pharmaceutical ingredients were developed more than 20 years ago. Isoxazolines, which fir...
Primary cations of the form XCH2CH2 (1) are unstable with respect to the bridged isomer cyclo-(CH2)2X (2) or the hydride-shift isomer CH3CHX (3).Two independent hydrogen isotope experiments for X ) OH demonstrate that gaseous HOCH2CH2 (1a) gives less of its bridged isomer, protonated oxirane (2a), than of its hydride-shift isomer, protonated acetaldehyde (3a).Metastable ion decompositions of io...
ISSN: 2410-9649 Asif, M., / Chemistry International 1(4) (2015) 174-183 www.iscientic.org 175 www.bosaljournals/chemint/ [email protected] Dimroth rearrangement. 1,2,3-triazole is considered to be the most useful component, widely used in research purpose as a building block for complex chemical compounds such as pharmaceutical drugs like tazobactam (Kaplancikli et al., 2005; Karakurt ...
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