In this paper we address the problem of nuclear segmentation in cancer tissue images, that is critical for specific protein activity quantification and for cancer diagnosis and therapy. We present a fully automated morphology-based technique able to perform accurate nuclear segmentations in images with heterogeneous staining and multiple tissue layers and we compare it with an alternate semi-au...

The cosmetic result is an important endpoint for breast cancer conservative treatment (BCCT), but the verification of this outcome remains without a standard. Objective assessment methods are preferred to overcome the drawbacks of subjective evaluation. In this paper a novel algorithm is proposed, based on support vector machines, for the classification of ordinal categorical data. This classif...

and Applied Analysis 3 The quasi-uniform space X,U will always be considered to be a topological space with the topology obtained by using as the family of all neighborhoods of a point x0 ∈ X all sets of the formU x0 {x ∈ X : x0, x ∈ U}, whereU runs overU. Such a topology is called topology of the quasi-uniformity. Note that each topology onX is induced by a quasi-uniformity see 8, 9 , the most...

Distributed Hash Tables (DHTs) are widely used for indexing and locating many types of resources, including semi-structured data modeled as XML documents. A common distributed strategy to process an XML query over a DHT consists in splitting it into a set of simple path queries, and resolving each of them separately. The traffic generated by this strategy grows with the number of paths in the q...

Continuous modification of the protein composition at synapses is a driving force for the plastic changes of synaptic strength, and provides the fundamental molecular mechanism of synaptic plasticity and information storage in the brain. Studying synaptic protein turnover is not only important for understanding learning and memory, but also has direct implication for understanding pathological ...

The Lab-on-a-Chip (LoC) described here is designed for the complex analysis of cytotoxic effects of chemical substances imposed on human keratinocytes. This LoC operating in real-time will have promising applications in cosmetic and pharmaceutical industries. All parameters and conditions on the LoC were optimized with respect to practical aspects under semi-automated conditions. The system inc...

Title: Semi-automated quantification of hard exudates in colour fundus photographs diagnosed with diabetic retinopathy Authors: Abhilash Marupally ([email protected]) Kiran Vupparaboina ([email protected]) Hari Peguda ([email protected]) Ashutosh Richhariya ([email protected]) Soumya Jana ([email protected]) Jay Chhablani ([email protected]) Version: 1 Date: 17 Aug 2017 Author’s...

Many physiological processes and pathological conditions in livers are spatially heterogeneous, forming patterns at the lobular length scale or varying across the organ. Steatosis, a common liver disease characterized by lipids accumulating in hepatocytes, exhibits heterogeneity at both these spatial scales. The main goal of the present study was to provide a method for zonated quantification o...