نتایج جستجو برای: selenium

تعداد نتایج: 14746  

Journal: :Clinical endocrinology 2013
Anne Drutel Françoise Archambeaud Philippe Caron

The thyroid is the organ with the highest selenium content per gram of tissue because it expresses specific selenoproteins. Since the discovery of myxoedematous cretinism and thyroid destruction following selenium repletion in iodine- and selenium-deficient children, data on links between thyroid metabolism and selenium have multiplied. Although very minor amounts of selenium appear sufficient ...

Journal: :Cancer research 1980
M S Wortzman H J Besbris A M Cohen

Male weanling Charles River CD rats were fed a Torula yeast based selenium-deficient diet or the same diet supplemented with selenium (0.5 ppm), as sodium selenite. Animals fed the basal diet for 3 weeks developed a functional selenium defi ciency as evidenced by an almost total loss of hepatic, sele nium-dependent glutathione peroxidase (glutathione:H2O2 ox idoreductase, EC i .1i .i .9) activi...

Journal: :The American journal of clinical nutrition 2016
Jinyuan Mao Jessica J Vanderlelie Anthony V Perkins Christopher W G Redman Kourosh R Ahmadi Margaret P Rayman

BACKGROUND Low selenium status in pregnancy has been associated with a number of adverse conditions. In nonpregnant populations, the selenium status or response to supplementation has been associated with polymorphisms in dimethylglycine dehydrogenase (DMGDH), selenoprotein P (SEPP1) and the glutathione peroxidases [cytosolic glutathione peroxidase (GPx1) and phospholipid glutathione peroxidase...

2016
Jinyuan Mao Jessica J Vanderlelie Anthony V Perkins Christopher WG Redman Kourosh R Ahmadi Margaret P Rayman

Background: Low selenium status in pregnancy has been associated with a number of adverse conditions. In nonpregnant populations, the selenium status or response to supplementation has been associated with polymorphisms in dimethylglycine dehydrogenase (DMGDH), selenoprotein P (SEPP1) and the glutathione peroxidases [cytosolic glutathione peroxidase (GPx1) and phospholipid glutathione peroxidas...

Journal: :international journal of nano dimension 0
m. kargar razi department of chemistry, north tehran branch-islamic azad university, tehran, iran. r. sarraf maamoury department of chemistry, tarbiat modares university, tehran, iran. s. banihashemi department of chemistry, north tehran branch-islamic azad university, tehran, iran.

in this study, selenium was recovered from an industrial dust. after the purification process, the researchers were able to prepare selenium micro powder. the objective of this study was to prepare selenium nano particles by water solution phase method from the micro powders. the results showed that selenium micronized powder and nano particles had high purity. the obtained nanoparticles were t...

Journal: :The American journal of clinical nutrition 2012
Rachel Hurst Lee Hooper Teresa Norat Rosa Lau Dagfinn Aune Darren C Greenwood Rui Vieira Rachel Collings Linda J Harvey Jonathan A C Sterne Rebecca Beynon Jelena Savović Susan J Fairweather-Tait

BACKGROUND Prostate cancer is a growing public health problem. Several human studies have shown a potentially protective effect of selenium, but the conclusions from published reports are inconsistent. OBJECTIVE The objective was to examine the evidence for relations between selenium intake, selenium status, and prostate cancer risk. DESIGN This was a systematic review and meta-analysis of ...

Journal: :The Journal of biological chemistry 1990
N Q Li P S Reddy K Thyagaraju A P Reddy B L Hsu R W Scholz C P Tu C C Reddy

Selenium-dependent glutathione peroxidase (Se-GSH-Px, GSH-H2O2 oxidoreductase EC 1.11.1.9) is the best characterized selenoprotein in higher animals, but the mechanism whereby selenium becomes incorporated into the enzyme protein remains under investigation. To elucidate the mechanism of insertion of selenium into Ge-GSH-Px further, we have systematically analyzed and compared the results of We...

Journal: :Analytical and bioanalytical chemistry 2006
Erik H Larsen Ryszard Lobinski Karin Burger-Meÿer Marianne Hansen Rafal Ruzik Lena Mazurowska Peter Have Rasmussen Jens J Sloth Olga Scholten Chris Kik

The scope of the work was to investigate the influence of selenate fertilisation and the addition of symbiotic fungi (mycorrhiza) to soil on selenium and selenium species concentrations in garlic. The selenium species were extracted from garlic cultivated in experimental plots by proteolytic enzymes, which ensured liberation of selenium species contained in peptides or proteins. Separate extrac...

Journal: :Cancer research 1985
R A LeBoeuf B A Laishes W G Hoekstra

Studies were conducted in vivo with regenerating liver and in vitro with mammalian cells to determine the effects of selenium on cell proliferation and the stages of the cell cycle affected by selenium. Six ppm selenium as Na2SeO3 fed to weanling male F344 rats for 6 wk significantly reduced the percentage of 3H-labeled hepatocyte nuclei by one-half compared to 0.1 ppm selenium when [methyl-3H]...

Journal: :Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2016
Li-Yun Wang Jian-Hua Yi Hang-Chao Xu Xiao-Fang Wu Dan-Yang Li Jing Han

OBJECTIVE To investigate the effect of low-selenium diet on the liver and kidneys of rats and explore the role of macrophage polarization into M1 and M2 phenotypes in liver and kidney injuries. METHODS Twenty-four rats (12 female and 12 male) were randomly divided into control group and low-selenium group and fed with normal chow (dietary selenium of 0.18 mg/kg) and low-selenium diet (dietary...

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