BACKGROUND Antidepressants (ADs) are known to have the potential to cause various cardiovascular adverse drug reactions (ADRs). The tricyclic antidepressants (TCAs) were first revealed to be a possible source of cardiovascular ADRs. In recent years, newer classes of ADs were also suggested to have a higher risk of cardiovascular adverse effects. In particular, the selective serotonin reuptake i...

OBJECTIVE THIS STUDY COMPARED ADHERENCE AND PERSISTENCE OF THREE BRANDED ANTIDEPRESSANTS: the serotonin and norepinephrine reuptake inhibitors (SNRIs) duloxetine and venlafaxine XR, and the selective serotonin reuptake inhibitor (SSRI) escitalopram; and generic selective SSRIs, and examined demographic and clinical predictors of adherence and persistence in patients with major depressive disord...

Objective: Epilepsy is a devastating neurological disorder with several cognitive or psychiatric comorbidities, including anxiety, autism spectrum disorder, and depressive disorder. It known that long-term drug treatment in epileptic patients increases the incidence of depression. Thus, epilepsy who later developed symptoms usually require to use antidepressant medication throughout their treat...

Isacsson G, Holmgren P, Ahlner J. Selective serotonin reuptake inhibitor antidepressants and the risk of suicide: a controlled forensic database study of 14,857 suicides. Acta Psychiatr Scand 2005;111:286–90. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Depression, as one of the largest influence disorders, needs more attention on its growing patients. Medicine treatment has been seeing major for depression. As most commonly used medicine, Selective Serotonin Reuptake Inhibitors (SSRIS) increases serotonin levels to treat depression effectively, and data from clinical prove value. Furthermore, Norepinephrine (SNRIs) Monoamine Oxidase (MAOIs) b...

Introduction: Unambiguous definition of mental disorders is difficult, mainly because the heterogeneity this group diseases and clarity line between pathology normal. The proposed by World Health Organization (WHO) widely accepted. In practice, definitions from legislation a country are also important. Aim work: purpose study to discuss basic issues diagnosis treatment disorders. Material metho...

Escitalopram (escitalopram oxalate; Cipralex(®), Lexapro(®)) is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of major depressive disorder (MDD) and anxiety disorder. This drug exerts a highly selective, potent, and dose-dependent inhibitory effect on the human serotonin transport. By inhibiting the reuptake of serotonin into presynaptic nerve endings, this drug enhance...