Elevated MPO (myeloperoxidase) levels are associated with multiple human inflammatory pathologies. MPO catalyses the oxidation of Cl-, Br- and SCN- by H2O2 to generate the powerful oxidants hypochlorous acid (HOCl), hypobromous acid (HOBr) and hypothiocyanous acid (HOSCN) respectively. These species are antibacterial agents, but misplaced or excessive production is implicated in tissue damage a...

The molar conductivity data of 1-butyl-3-methylimidazolium salicylate, [BMIm][Sal] as an active pharmaceutical ingredient ionic liquid (API-IL) have been determined in water and aqueous solutions of amino acids, glycine and L-alanine at T= (288.15 to 318.15) K. The molar conductivity data were analyzed by low concentration Chemical Model (lcCM) and limiting molar conductivities ( ), ion associa...

The room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis-(trifluorometanesulfonyl)imide BMIm[NTf₂] was used as a novel medium for improvement of separation and quantization of 16 aromatic amines typically present as contaminants in consumer products and detected by HPLC coupled to an electrochemical detector. The aromatic amines, namely 4,4'-diaminodiphenylmethane, 4-chloroaniline...

The spread and propagation of antibiotic resistance genes (ARGs) is a worldwide public health concern. Ionic liquids (ILs), considered as "environmentally friendly" replacements for industrial organic solvents, have been widely applied in modern industry. However, few data have been collected regarding the potential ecological and environmental risks of ILs, which are important for preparing fo...

The electrochemistry of Mg salts in room-temperature ionic liquids (ILs) was studied using plating/stripping voltammetry to assess the viability of IL solvents for applications in secondary Mg batteries. Borohydride (BH4(-)), trifluoromethanesulfonate (TfO(-)), and bis(trifluoromethanesulfonyl)imide (Tf2N(-)) salts of Mg were investigated. Three ILs were considered: l-n-butyl-3-methylimidazoliu...

This paper looks a t the polic y implic a tions of v iewing innov a tion a s a system ic phenomenon. The ® rst sec tion prov ides a br ief overv iew of conceptua l approa c hes used in the rec ent litera ture on innov a tion systems. The sec ond pa r t of the paper looks a t lea rning a nd tec hnologic a l knowledge a t the ® rm-lev el, a nd explores the ways in which different theoretica l a p...

We analyze radial velocities for a sample of 31 Class I and flat spectrum protostars in TaurusAuriga, ρ Ophiuchi and Serpens for evidence of the global dynamical state of extremely young stellar populations buried within parental molecular clouds. Comparing the radial velocity of each protostar to that of the local CO gas, we are able to constrain the one dimensional radial velocity dispersion ...

Background: Corynebacterium glutamicum (C. glutamicum) is a potential host for the secretory production of the heterologous proteins. However, to this date few secretion-type gene expression systems in C. glutamicum have been developed, which limit applications of C. glutamicum in a secretory production of the heterologous proteins.Objectives: In this stu...

The effects of repulsive interaction on the electric double layer (EDL) and differential capacitance (Cd) of an ionic liquid (IL) 1-butyl-3-methyl-imidazolium hexafluorophosphate (BMIM(+)/PF6(-)) on the graphite electrode were studied by molecular dynamics (MD) simulations. The strength of repulsive interaction was studied by manually tuning the parameter lambda (λ) with λ = 1.00 for normal Len...

O desempenho de duas lipases nativas (lipase de Aspergillus niger e Rhizopus oligosporus), e a influência da temperatura, doador acila (acetato de etila, acetato de vinila, acetato de iso-propenila e anidrido acético) e do meio orgânico foi avaliado na resolução da (RS)-feniletilamina (1). O efeito de anions em uma série de líquidos iônicos (LIs) baseados em derivados do imidazol [BMIm][X], ond...