BACKGROUND It is well recognized that the season of the year exerts an influence on some diseases and causes of death such as coronary heart diseases, stroke, infectious diseases and so on. METHODS We evaluated the influence of seasonal changes on diseases and causes of death in Japan using the Japan Vital Statistics from 1970 to 1999 and recorded weather data (mean temperature), by a Fourier...

Punctuated antigenic change is believed to be a key element in the evolution of influenza A; clusters of antigenically similar strains predominate worldwide for several years until an antigenically distant mutant emerges and instigates a selective sweep. It is thought that a region of East-Southeast Asia with year-round transmission acts as a source of antigenic diversity for influenza A and se...

BACKGROUND During the course of development of montelukast, a cysteinyl leukotriene receptor 1 antagonist, for treatment of seasonal allergic rhinitis, a double-blind, non-inferiority study was carried out to evaluate the efficacy and safety of montelukast 5mg and 10mg compared with pranlukast 450mg, which has a similar mechanism of action. METHODS Montelukast 5mg, 10mg or pranlukast 450mg an...

Seasonal changes in behavior and in its underlying neural substrate are common across animal taxa. These changes are often triggered by steroid sex hormones. Song in seasonally breeding songbirds provides an excellent example of this phenomenon. In these species, dramatic seasonal changes mediated by testosterone and its metabolites occur in adult song behavior and in the neural circuitry contr...

[1] A large increase in near-infrared (NIR) reflectance of Amazon forests during the light-rich dry season and a corresponding decrease during the light-poor wet season has been observed in satellite measurements. This increase has been variously interpreted as seasonal change in leaf area resulting from net leaf flushing in the dry season or net leaf abscission in the wet season, enhanced phot...

One consequence of climate change is the alteration of global water fluxes, both in amount and seasonality. As a result, the seasonal difference between dry- (p < 100 mm/month) and wet-season (p > 100 mm/month) precipitation (p) has increased over land during recent decades (1980-2005). However, our analysis expanding to a 60-year period (1950-2009) showed the opposite trend. This is, dry-seaso...

Recently, in the Auerswald et al. (2015) comment on "Rainfall erosivity in Europe", 5 criticisms were addressed: i) the neglect of seasonal erosion indices, ii) the neglect of published studies and data, iii) the low temporal resolution of the data, especially of the maximum rain intensity, iv) the use of precipitation data instead of rain data and the subsequent deviation of the R-factor in Ge...

Reproductive success usually declines in the course of the season, which may be a direct effect of breeding time, an effect of quality (individuals with high phenotypic or environmental quality breeding early), or a combination of the two. Being able to distinguish between these possibilities is crucial when trying to understand individual variation in annual routines, for instance when to bree...

As we start a new school year I would like to take this opportunity to welcome back the many students, staff, research associates and faculty associated with the Center for the Integrative Study of Animal Behavior (CISAB). To those of you who are new to CISAB and the Indiana University community, I would like to extend a special welcome to you and I would also like to express my excitement abou...