the genotypes of the melatonin receptor 1a (mtnr1a) were determined by pcr-rflp in the native iranian shall  and karakul breeds of sheep . blood samples were collected from 60 karakul and 50 shall breeds. genomic dna was extracted based on the guanidin thiocyanate-slica gel method. after pcr reaction, pcr products were digested by the mnl1 restriction enzyme. the mtnr1a locus had two genotypes ...

The merits of the modelling philosophy of Box & Jenkins (1970) are illustrated with a summary of our recent work on seasonal river flow forecasting. Specifically, this work demonstrates that the principle of parsimony, which has been questioned by several authors recently, is helpful in selecting the best model for forecasting seasonal river flow. Our work also demonstrates the importance of mo...

In my opinion, the main handicap of this study is an inadequate dataset used for the stated objectives. The authors are trying to describe a seasonal signal, as well as discern a seasonal signal from short-term intra-seasonal decay events, using data from a single year. The (roughly) bi-monthly sampling regime is inadequate to capture meaningful data on the sub-seasonal events. The records capt...

Seasons are the complex nonlinear response of the physical climate system to regular annual solar forcing. There is no a priori reason why they should remain fixed/invariant from year to year, as is often assumed in climate studies when extracting the seasonal component. The widely used econometric variant of Census Method II Seasonal Adjustment Program (X-11), which allows for year-to-year var...

Punctuated antigenic change is believed to be a key element in the evolution of influenza A; clusters of antigenically similar strains predominate worldwide for several years until an antigenically distant mutant emerges and instigates a selective sweep. It is thought that a region of East-Southeast Asia with year-round transmission acts as a source of antigenic diversity for influenza A and se...

BACKGROUND Although there was a report about the seasonal variation in Wuhan city, it only analyzed the prevalence data of pulmonary tuberculosis (TB) cases, and just studied the seasonality by subgroup of smear positive and negative from 2006 to 2010 by spectral analysis. In this study, we investigated the seasonality of the total newly notified pulmonary TB cases by subgroups such as time per...

Cytokine responses play an important role in the pathogenesis of influenza infection. Previous studies found that cytokine expressions in patients infected with the novel A (H1N1) influenza virus (nvA (H1N1)) could reflect the severity of the disease. But the patterns of cytokine response in patients infected with seasonal influenza virus and the correlations between cytokine responses and clin...

Introduction Conclusions References Tables Figures Back Close Abstract Introduction Conclusions References Tables Figures Back Close Abstract A seasonal-trend decomposition technique based on a locally-weighted regression smoothing (Loess) approach has been used to decompose monthly ozone concentrations at Mace Head (Ireland) into trend, seasonal and irregular components. The trend component sh...

BACKGROUND Cardiovascular diseases (CVD) mortality has been shown to follow a seasonal pattern. Several studies suggested several possible determinants of this pattern, including misclassification of causes of deaths. We aimed at assessing seasonality in overall, CVD, cancer and non-CVD/non-cancer mortality using data from 19 countries from different latitudes. METHODS AND FINDINGS Monthly mo...

This study compares two new seasonal adjustment methods designed to handle outliers and structural changes: X-IZARIMA and GAUSUM-STM. X12-ARIMA is a successor to the X-ll-ARIMA seasonal adjustment method, and is being developed at the U.S. Bureau of the Census (Findley et al. (1988)). GAUSUM-STM is a non-Gaussian method using time series structural models, and was developed for this study based...