After tenotomy adjoining 3 o'clock and 9 o'clock limbus, 3-mm-wide partial-thickness scleral tunnels are created at these two diametrically opposite points 3 mm from the limbus such that they reach up to a distance of 1.5 mm from the limbus. Two ab externo sclerotomies are created using 26-G needles on the bed of these partial-thickness scleral tunnels. Precaution is taken to ensure that the po...

PURPOSE To further understand postoperative complications after vortex vein damage during scleral buckling surgery. METHODS The records of 34 patients (34 eyes) with vortex vein damage during scleral buckling surgery for rhegmatogenous retinal detachment were reviewed and compared with the records of 410 eyes undergoing similar surgery without vortex vein damage. RESULTS Postoperative compl...

PURPOSE To study the response of scleral cold receptors located in areas of the eye unexposed to temperature and blood flow changes. METHODS In anesthetized cats, the neural activity was recorded from single, cold-sensory fibers of the ciliary nerves innervating the sclera and limbus. Controlled temperature changes of the receptive field were performed with a contact thermode. Ocular blood fl...

IMPORTANCE Recognition of posterior scleral bowing with choroidal nevus is essential to avoid an underestimation of tumor thickness. OBJECTIVE To describe a particular observation of posterior scleral bowing associated with choroidal nevus on enhanced-depth imaging (EDI) optical coherence tomography (OCT). DESIGN, SETTING, AND PARTICIPANTS Retrospective observational case series at a referr...

PURPOSE The purpose of this study was to examine the possibility that all-trans-retinoic acid (RA) in the eye is a signal related to changes in scleral extracellular matrix in a primate model of postnatal eye growth. METHODS Juvenile marmosets (Callithrix jacchus) were divided into two experimental groups based on their response to monocular deprivation with diffusers: group 1, treated eyes b...

We present experimental results and computer modeling on the optical properties of the human scleral tissue. The wavelength dependence of the refractive index of collagen fibers in the human scleral tissue was estimated on the base of Mie theory. Dispersion formula describing this dependence was derived. The results are general and can be used to describe optical properties of many other fibrou...

The literature on intra-ocular pressure dynamics is reviewed, including tonometer design and calibration, the influence of corneal-scleral mechanics, and scleral rigidity factors. Drugs that influence the outflow facility of the trabecular meshwork (TM) are discussed. Transmural pressure drop across the lamina cribosa (LC) is an important parameter, in terms of quantifying potential glaucoma da...

RATIONALE This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of goo...

AIMS To characterise lamina cribrosa and anterior scleral canal wall architecture in pressurised (IOP 10 mm Hg) and non-pressurised (IOP 0 mm Hg) normal monkey eyes. METHODS Eight normal eyes from eight monkeys were enucleated before sacrifice and the optic nerve heads (ONH) trephined and immersion fixed in glutaraldehyde (IOP 0). Nine normal eyes from nine monkeys were perfusion fixed in sit...

Increasing evidence suggests that unknown collagen remodeling mechanisms in the sclera underlie myopia development. We are proposing a novel organ culture system in combination with two-photon fluorescence imaging to quantify collagen remodeling at the tissue- and lamella-level. Tree shrew scleral shells were cultured up to 7 days in serum-free media and cellular viability was investigated unde...