نتایج جستجو برای: sbh
تعداد نتایج: 308 فیلتر نتایج به سال:
In this letter, we discuss how thermal fluctuations can effect the stability of (generally) charged black holes when close to certain critical points. Our novel treatment utilizes the black hole area spectrum (which is, for definiteness, taken to be evenly spaced) and makes an important distinction between fixed and fluctuating charge systems (with these being modeled, respectively, as a canoni...
Aroylhydrazones derived from salicylaldehyde are compounds with interesting biological properties including a high anticancer activity. Salicylaldehyde benzoylhydrazone (SBH) is an unusually potent inhibitor of DNA synthesis and cell growth in a variety of cultured human and rodent cells. Various derivatives of SBH have been synthesized in order to discover new more effective antiproliferative ...
Investigation of proteinuria, whose pathophysiology remains incompletely understood, is confounded by differences in the phenotype between males and females. We initiated a sex-specific geno-transcriptomic dissection of proteinuria in uninephrectomized male and female Sabra rats that spontaneously develop focal and segmental glomerulosclerosis, testing the hypothesis that different mechanisms m...
A new, scalable interconnection topology called the Spanning Multichannel Linked Hypercube (SMLH) is proposed. This proposed network is very suitable to massively parallel systems and is highly amenable to optical implementation. The SMLH uses the hypercube topology as a basic building block and connects such building blocks using two-dimensional multichannel links (similar to spanning buses). ...
The pathophysiology underlying proteinuria remains incompletely understood and warrants further research. We currently initiated the investigation of the genetic basis of proteinuria in the Sabra rat, a model of salt susceptibility that we showed previously to be also a model of spontaneous proteinuria that is unrelated to salt loading or development of hypertension. We applied the total genome...
Maria Daniela D'Agostino,1,2 Andrea Bernasconi,1 Soma Das,5 Alexandre Bastos,1 Rosa M. Valerio,1,10 Andre Palmini,11 Jaderson Costa da Costa,11 Ingrid E. Scheffer,13 Samuel Berkovic,1,13 Renzo Guerrini,14 Charlotte Dravet,15 Jiro Ono,16 GianLuigi Gigli,17 Antonio Federico,18 Fran Booth,4 Bruno Bernardi,19 Lilia Volpi,19 Carlo Alberto Tassinari,19 Mary Anne Guggenheim,6 David H. Ledbetter,5 Jos...
Rho-GTPases have been found to be crucial for cytoskeleton remodelling and cell polarity, as well as key players in directed cell migration in various tissues and organs, therefore becoming good candidates for involvement in neuronal migration disorders. We recently found that genetic deletion of the small GTPase RhoA in the developing mouse cerebral cortex results in three distinct cortical ma...
Recent experiment has uncovered semimetal bismuth (Bi) as an excellent electrical contact to monolayer MoS$_2$ with ultralow resistance. The physics of the broader semimetal/monolayer-semiconductor family beyond Bi/MoS$_2$, however, remains largely unexplored thus far. Here we perform a comprehensive first-principle density functional theory investigation on properties between six archetypal tw...
A new final endpoint of complete gravitational collapse is proposed. By extending the concept Bose–Einstein condensation to systems, a static, spherically symmetric solution Einstein’s equations obtained, characterized by an interior de Sitter region p=−ρ vacuum condensate and exterior Schwarzschild geometry arbitrary total mass M. These are separated phase boundary with small but finite thickn...
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