endoplasmic reticulum has a critical role in the synthesis and folding of secretory and membrane proteins. high accumulation of proteins in er activates the unfolded protein response and glucose regulated protein 78 or gpr78 plays an essential role in this pathway.  unfolded protein response is activated in cancerous cells due to their adverse condition to survive and it has been shown that grp...

the modeling investigation in this paper discusses the system level effects of a toxicant on a three species food chain system. in the models, we have assumed that the presence of top predator reduces the predatory ability of the intermediate predator. the stability analysis of the models is carried out and the sufficient conditions for the existence and extinction of the populations under the ...

the relation between microchimerism and allograft tolerance is still a mystery. in this study we determined the presence of peripheral blood microchimerism (pbmc) in female renal transplant recipients from living male donors with second round polymerase chain reaction (pcr). second round pcr was used to find y chromocome products. the degree of pbmc in renal transplant recipinents must be below...

in this paper, the effect of size on melting temperature of metallic nanoparticles (au, pb and bi) is theoretically simulated and explained. in this regard, the cause of difference in various experimental data is introduced, which is the difference between nanoparticles’ grain gaussian distribution. this volume-depended model with the help of the gaussian distribution can describe the relation ...

gabapentin (gpn) is a new antiepileptic agent currently in used as add-on therapy in adult patients suffering from partial seizures. the extent of liver damage at different dosage and long term treatment with gpn is not yet clear. therefore this study was undertaken to find out the possibility of liver damage by this drug. adult male (wistar) rats of 180-220 g were administered intraperitoneall...

the effectiveness of an enzymatic cocktail, collagenase and trypsin, on the absorptive function of ilealsegment was studied to evaluate the changes within groups after performing ileocystoplasty in an animalmodel. twenty-one female mixed-bred persian dogs were randomized into 7 groups. the groups included: 1) negative control group (ncg) in which no ileocystoplasty was performed (n = 3); 2) pos...

nowadays multicriteria decision making (mcdm) methods are a useful tool for investigating natural resources and toaddress problems related to hydro systems. the goal of this research was to assess the daliri standardization method(dsm) to prioritize and make selections for application to mcdm. and to compare the dsm method with the utilityadditive (uta) method. the (dsm) method, unlike the (uta...

conclusions there was a decrease in cognitive function, including attention, visual memory, naming, and executive function, as well as psychomotor function among residents of department of anesthesiology and intensive care, faculty of medicine, universitas indonesia, who underwent 12 working hours. results cognitive stimulation” test revealed statistically significant decrease at sequential ima...

objectives: the objective behind this study was investigating the relationships between family functioning and psychological hardiness in parents of exceptional children versus parents of normal children. methods: the study was causal-comparative. population included all parents of normal and exceptional students in bojnurd city studying in ordinary and exceptional schools in the academic year ...

Using the idea behind the Tillich-Zémor hash function, we propose a new hash function. Our hash function is parallelizable and its collision resistance is implied by a hardness assumption on a mathematical problem. Also, it is secure against the known attacks. It is the most secure variant of the Tillich-Zémor hash function until now.