The frequency-domain multiple-distance (FDMD) method is capable of measuring the absolute absorption and reduced scattering coefficients of optically turbid media. Absolute measurement of absorption at two near-infrared (NIR) wavelengths makes possible the quantitation of tissue haemoglobin concentration and tissue haemoglobin oxygen-saturation (StO2). However, errors are introduced by the unce...

OBJECTIVES Exercise testing in patients with cystic fibrosis (CF) has become an important tool in assessing disease severity and predicting overall outcome. The reproducibility of maximal exercise testing was examined in adult subjects with stable CF. METHODS Nine subjects with CF underwent a total of three maximal exercise tests carried out under identical circumstances over a 28-day period....

Since oxygen has to be given to most children in developing countries on the basis of clinical signs without performing blood gas analyses, possible clinical predictors of hypoxaemia were studied. Sixty nine children between the ages of 2 months and 5 years admitted to hospital with acute lower respiratory tract infection and an oxygen saturation (Sao2) < 90% were compared with 67 children matc...

BACKGROUND The oxygen saturation of haemoglobin is reduced in high altitude-living organisms. Increase in the hematocrit is responsible for rise in the hemoglobin concentration so that the oxygen carrying capacity in the hypobaric hypoxic subject is elevated. OBJECTIVES To compare two different high altitude populations, in order to study the relationship between arterial oxygen saturation an...

The efficacy of melatonin in the treatment patients with coronavirus 2019 (COVID-19) is controversial. This review has summarized evidence on oral compared to placebo mild moderate COVID-19 infection. We searched four international online databases and all randomized clinical trials (RCTs) that investigated effects outcomes, including mortality, discharge time, O2 saturation (SaO2), c-reactive ...

We made an assessment of five pulse oximeters in regard to their ability to replace the HP ear oximeter as a noninvasive measurement of SaO2. Trials were performed during isocapnic progressive hypoxia (SaO2 range, 99 to 70 percent) in 22 white and six black subjects. Comparisons between values of SaO2 by oximetry were analyzed by comparing the difference of values by the two methods against the...

The reliability of various methods for detecting oesophageal intubation was assessed by means of a single blind study in rats. Both oesophagus and trachea were simultaneously intubated. The presence or absence of various clinical signs was noted during tracheal or oesophageal ventilation and arterial blood gases and end-tidal CO2 were measured. Oesophageal ventilation for one minute was associa...

BACKGROUND Hypoxemia is common in patients with cirrhosis but the natural history of this syndrome is unknown. This study was conducted to evaluate the natural history of arterial oxygenation in patient with end stage liver cirrhosis. METHODS Sixty eight patients with liver cirrhosis were followed up for 6-12 months. Arterial blood gas (ABG) and pulse oximetry were obtained on day of presenta...

Oronasopharyngeal suction (ONPS) with a suction bulb at birth is a traditional practice in the initial management of healthy infants in Iran and many other countries. The purpose of this study was to compare the effects of oronasopharyngeal suction (ONPS) with those of no suction in normal, term newborns delivered vaginally. A total of 170 healthy term infants of first and single uncomplicated ...

Near-infrared spectroscopy (NIRS) is increasingly used as a non-invasive technique for monitoring cerebral oxygenation and haemodynamics . Simple continuous-wave (CW) NIRS systems utilising differential spectroscopy can measure quantitative changes in oxyand deoxyhaemoglobin (∆[O2Hb], ∆[HHb]) but only from an arbitrary baseline. Numerous studies of changes in cerebral oxygenation and haemodynam...