BACKGROUND Small molecules classified as haptens are generally measured by competitive immunoassay, which is theoretically inferior to noncompetitive sandwich immunoassay in terms of sensitivity and specificity. We created a method for developing sandwich immunoassays to measure haptens on the basis of antimetatype antibodies. METHODS We generated antimetatype monoclonal antibodies against a ...

BACKGROUND Tropical fasciolosis caused by Fasciola gigantica infection is one of the major diseases infecting ruminants in the tropical regions of Africa and Asia including Thailand. Parasitological diagnosis of fasciolosis is often unreliable and possesses low sensitivity. Therefore, the detection of circulating parasite antigens is thought to be a better alternative for diagnosis of fasciolos...

Let d 2 D = {1, . . . , 9}, and let k be a positive integer with gcd(k, 10d) = 1. Define a sequence {sn(k, d)}n=1 by sn(k, d) := k dd . . . d | {z } n k. We say k is a d-composite sandwich number if sn(k, d) is composite for all n 1. For a d-composite sandwich number k, we say k is trivial if sn(k, d) is divisible by the same prime for all n 1, and nontrivial otherwise. In this paper, we develo...

Non-standard sandwich gravitational waves are constructed from the homogeneous pp vacuum solution and the motions of free test particles in the space-times are calculated explicitly. They demonstrate the caustic property of sandwich waves. By performing limits to impulsive gravitational wave it is demonstrated that the resulting particle motions are identical regardless of the “initial” sandwic...

BACKGROUND Brain natriuretic peptide (BNP) is an unstable molecule that can rapidly lose immunologic activity in blood. Conventional sandwich BNP immunoassays use 2 antibodies specific to 2 different epitopes. Larger distances between epitopes are associated with a greater probability of proteolysis sites being located between the antibody-binding sites, and thus such assays have an increased s...

The literature is inconclusive on the development of adjacent-level vertebral fracture after initial cement augmentation. A preliminary hypotheses is that cement injection exaggerates force transmission to the adjacent vertebral bodies, thereby predisposing those levels to future fractures. A sandwich vertebra is an intact vertebral body located between 2 previously cemented vertebrae. The purp...

Non-toxic sandwich: By trapping mercury nanodroplets between two graphene monolayers, a new type of two-dimensional sandwich electrode is realized, which non-toxic and stable with interesting electrochemical properties.

This paper investigates the difference between thickness of zinc-based alloys oxide films in dynamic condition using the oxide-metal-oxide (OMO) sandwich method and static condition by theoretical calculations. In dynamic condition, the thickness of the oxide film in the OMO sandwich sample was characterized by scanning electron microscopy (SEM). In the static condition, the thickness and type ...

Vibration behavior of different types of porous functionally graded (FG) conical sandwich shells are investigated based on a modified high order sandwich shells theory for the first time. Sandwich shell includes FG face sheets covering a homogeneous core and the second one includes homogeneous face sheets and a FG core. Power law rule modified by considering two types of porosity distributions ...

In this paper, we first establish a new fixed point theorem for a Meir-Keeler type condition. As an application, we derive a simultaneous generalization of Banach contraction principle, Kannan's fixed point theorem, Chatterjea's fixed point theorem and other fixed point theorems. Some new fixed point theorems are also obtained.