نتایج جستجو برای: sall4
تعداد نتایج: 329 فیلتر نتایج به سال:
INTRODUCTION Oral cancers are the 10th most common cancer worldwide, with oral tongue squamous cell carcinoma (OTSCC) having the highest incidence. Surgery and radiotherapy (RT), the mainstay treatments for OTSCC, impact on the patients’ quality of life and the 50% 5-year survival has remained unchanged for 40 years. Cancer stem cells (CSCs) have been proposed to be the origin of many cancers, ...
The scarcity of primordial germ cells (PGCs) in the developing mammalian embryo hampers robust biochemical analysis of the processes that underlie early germ cell formation. Here, we demonstrate that DAZL, a germ cell-specific RNA binding protein, is a robust PGC marker during in vitro germ cell development. Using Dazl-GFP reporter ESCs, we demonstrate that DAZL plays a central role in a large ...
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