RATIONALE Despite fast advances in ambient mass spectrometry imaging (MSI), the study of neutral and nonpolar compounds directly from biological matrices remains challenging. In this contribution, we explore the feasibility of laser ablation atmospheric pressure photoionization (LAAPPI) for MSI of phytochemicals in sage (Salvia officinalis) leaves. METHODS Sage leaves were studied by LAAPPI-t...

Sage (Salvia) species is known as the Functional Novel Natural Medicine, Salvia Extract are considered important for drug development, because they are reported to have Pharmacological activity in the Asia, Middle East especially China and India. For a long time Salvia has been used in traditional medicine for the relief of pain, protecting the body against oxidative stress, free radical damage...

Colorectal cancer (CRC) is a common malignancy and significant cause of mortality in Western societies. It develops through an accumulation of genetic and epigenetic alterations, transforming normal colon cells and giving them growth advantage. Epigenetic alterations are reversible and studies have shown that dietary compounds can alter the epigenetic status and reactivate epigenetically-silenc...

In this study, sage (Salvia officinalis L.), linden (Tilia platyphyllos Scop.), and daisy (Matricaria chamomilla L.) herbs, which have rich phytochemical content are frequently consumed in winter months for medicinal purposes, were obtained from three different herbalists located Bingol investigated terms of their heavy metal contents, total flavonoid, anthocyanin polyphenol contents. Some the ...

The genus Salvia L. has more than 900 species distributed throughout the globe. 21 are growing in Ukraine. All of this have essential oils. officinalis and sclarea been used culture widely medical practice. chemical composition other sage possibility their use pharmaceutical practice almost not studied. Taking into account results chemotaxonomic studies flora Ukraine, prevalence prospects for i...

The antioxidant activity and total phenolic content of some spices (M. piperita L., R. coriaria L., T. spicata, S. officinalis, R. officinalis L., C. ovata L., O. vulgare L., L. nobilis L. and C. annum L.) were determined. The higher TEAC values (mmol TE/g extract) were obtained for sage (1.783) and rosemary (1.241). The IC value (mg/ml) ranged between 0.103-4.082 for mint and capers, respectiv...