Sodium antimony gluconate (SAG) and miltefosine used in the treatment of kala-azar are known to cause several side effects but severe thrombocytopenia has not been reported. Four cases of severe thrombocytopenia, two caused by SAG and two by miltefosine were promptly detected and treated by immediate withdrawal of the offending drugs, platelet and blood transfusions and dexamethasone. After imp...

Modelling and simulation of semi-autogenous (SAG) mills are valuable tools for helping to design control laws for a given application and subsequently to optimise its performance and process control. SAG mills (see Figure 1) are presently one of the most widely used alternatives in the field of mineral size reduction as a result of their advantages such as higher processing capacity, lower phys...

Both superantigens (SAG) and many anti-TCR monoclonal antibodies (mAb) have specificity for the V beta region of the TCR encoded by TCRBV genes. For instance the bacterial SAG staphylococcal enterotoxin E (SEE), the retroviral SAG MTV-9 and the mAb OT145 each react with human T cells expressing BV6S7. This BV gene encodes two common alleles. We found that SEE and the mAb preferentially activate...

Active infection by T. gondii was evaluated by immunoassay for soluble SAG-1 (p30), the major surface antigen from T. gondii, specific antibodies and immune complexes in human cerebrospinal fluid (CSF) samples. A total of 263 samples of CSF were collected from hospitalized patients presenting neurological disorders and analyzed for antibodies to HIV. Patients were divided into two groups: HIV p...

This project presents a power quality improvement of unified power quality conditioner (UPQC) to compensate current and voltage quality problems of sensitive loads. The UPQC consists of the series and shunt converter having a common dc link. The series converter mitigates voltage sag from the supply side and shunt converter eliminates current harmonics from the nonlimear load side. The develope...

Classification, nomenclature and identification of the Streptococcus anginosus group (SAG) have been historically problematic and unreliable, mainly due to variability in bacteriological characteristics and clinical presentations. This group was first discovered in 1956 by Guthof, in reference to non-hemolytic streptococcal lassification, nomenclature and identification of the Streptococcus ang...

BACKGROUND Previous studies have reported a higher prevalence of immunoglobulin E (IgE) specific for staphylococcal superantigens (SAg) in the nasal mucosa of patients with aspirin-exacerbated respiratory disease (AERD), associated with eosinophilic inflammation and leukotriene production. However, the role of SAg-specific IgE in the pathogenesis of AERD is not well understood. We evaluated the...

Life-threatening infections caused by Staphylococcus aureus, particularly the community-acquired methicillin-resistant strains of S. aureus, continue to pose serious problems. Greater virulence and increased pathogenicity of certain S. aureus strains are attributed to higher prevalence of exotoxins. Of these exotoxins, the superantigens (SAg) are likely most pathogenic because of their ability ...

INTRODUCTION The irradiation of blood components is used to inactivate T-lymphocytes to prevent transfusion-associated graft-versus-host (GVH) disease in susceptible recipients. X-irradiation can be used as an alternative to gamma irradiation and does not involve the use of a radioactive source. This study investigated the effect of X-irradiation on the quality of various red cell concentrates ...

The purpose of this study is to investigate the effect of 16 weeks step-aerobic exercises and core exercises on left ventricular structure and function with some physiological parameters in sedentary women. Methods To achieve the purpose of this study, a total of 45 volunteers including (step-aerobic group (SAG, n = 25), core exercise group (CEG, n = 20) were selected as participants. Two dif...