background & aim: saffron is one of the expensive spices known since antiquity for its color, flavor and medicinal properties. saffron is the dried stigma of crocus sativus plant. the three basic components of the stigma on which the qualitative characteristics of saffron depend are crocin (color), picrocrocin (taste), and safranal (aroma). the quality of saffron is a function of climatic c...

Objective: There are different pathophysiological mechanisms for obsessive- compulsive disorder (OCD) as suggested by the serotonergic, dopaminergic, and glutamatergic hypotheses. The present study aimed at comparing the efficacy and safety of saffron (stigma of Crocus sativus) and fluvoxamine in the treatment of mild to moderate obsessive- compulsive disorder. Method: In this study, 50 males a...

Mitochondrial dysfunction is the key pathogenic mechanism of cerebral injury induced by high-altitude hypoxia. Some Chinese herbal monomers may exert anti-hypoxic effects through enhancing the efficiency of oxidative phosphorylation. In this study, effects of 10 kinds of Chinese herbal monomers on mitochondrial respiration and membrane potential of cerebral mitochondria isolated from hypoxia-ex...

Due to dynamic nature of current software development methods, changes in requirements are embraced and given proper consideration. However, this triggers the rank reversal problem which involves re-prioritizing requirements based on stakeholders’ feedback. It incurs significant cost because of time elapsed in large number of human interactions. To solve this issue, a Semi-Automated Framework f...

Production of Saffron (Crocus sativus L.) is expanding in both the traditional and non-native areas Jammu Kashmir, India. A study was carried out to develop a cost-effective production system module at ARSSSS, SKUAST-Kashmir, Pampore determine suitable corm weight planting density for saffron. The treatments current includes 3 levels (W1= < 8g, W2= 8-12g W3 = >12g) 5 densities viz., 15 lakh den...

Host–microbiome interactions are specific and not random, making them defining entities for the host. The hypothesis proposed by various researchers earlier, that both plants animals harbor inheritable core microbiome, is being augmented in present study. Additionally, a case using microbial fingerprint as biomarker, only plant identification but also geographical indicator, has been investigat...

objective(s): ischemia/reperfusion (i/r) injury of spinal cord is leading to the paraplegia observed. in this study, we investigated the protective effect of the saffron extract on spinal cord i/r injury. materials and methods: thirty five male sprague-dawley rats were divided into 5 groups: intact, sham surgery, normal saline (ns), low dose saffron aqua extract, high dose saffron aqua extract....

the separation of saffron stigmas from fresh flowers is the most important and the most difficult stage of saffron harvesting. saffron production costs are high because this harvesting stage is done by hand and is very time-consuming. one way of preserving the saffron flower is to dry it. the separating of the stigma from dried saffron flowers can then be done at an appropriate time. this study...

Recent decades have seen development of research and an increased interest in the psychopharmacology of natural remedies. More than 20 herbal remedies have been identified that may potentially be applied in medicine as antidepressive, anxiety relieving or sleep-inducing agents. Patients often prefer to take herbal remedies and often take them on their own, without consulting a physician. The ai...