Nitric oxide (NO) functions as an endothelium-derived relaxing factor by activating guanylate cyclase to increase cGMP levels. However, NO and related species may also regulate vascular tone by cGMP-independent mechanisms. We hypothesized that naturally occurring NO donors could decrease the pulmonary vascular response to serotonin (5-HT) in the intact lung through chemical interactions with 5-...

OBJECTIVE The purpose of this study is to evaluate the effect of ethyl pyruvate (EP) on systemic inflammatory response and lung injury in an experimental rat model of ruptured abdominal aortic anurysm (RAAA). METHODS Anaesthetized 30 Sprague-Dawley male rats were randomized to sham (Sh n : 6) (Sh + EP n : 6) or shock and clamp (S/C) groups (S/C n : 9) (S/C + EP n : 9). In the S/C and S/C + EP...

[Purpose] Video-assisted thoracic surgery and preoperative pulmonary rehabilitation are effective in preventing postoperative complications in patients with cardiopulmonary disease. The present study aims to elucidate the presence of postoperative pneumonia and atelectasis in patients with nontuberculous mycobacterial lung disease who underwent lung resection with video-assisted thoracic surger...

A new technique for combinational circuit optimization is described in the context of S-boxes. The technique is a two-step process. In the first step, the non-linearity of the circuit – as measured by the number of non-linear gates it contains – is reduced. The second step reduces the number of gates in the linear components of the already reduced circuit. The technique can be applied to arbitr...

In this paper a robust test statistic for testing between two income distributions is analysed. Victoria-Feser (1996) proposed a robust version of the classical test based on the comparison of the maximised likelihood functions for the two models (Cox 1961, 1962). She showed its robustness properties as well as other properties. She also proposed an algorithm for the computation of the robust C...

Objective(s): Umbelliprenin is a prenyloxy-coumarin with pharmacologically polyvalent activity. Several studies have shown its anti-inflammatory, anti-tumor, antioxidant, and antigenotoxic activity, and other functions. However, the exact mechanism of action of this compound on the immune response has not yet been shown. Here, we investigated umbelliprenin effects on the predominance of Th1 and...

It has long been known that G protein-coupled receptors (GPCR) are subject to illegitimate expression in tumor cells. Presumably, hijacking the normal physiologic functions of GPCRs contributes to all biologic capabilities acquired during tumorigenesis. Here, we searched for GPCRs that were expressed in lung cancer: the mRNA encoding orphan G protein-coupled receptor 19 (GPR19) was found freque...

in this paper, we consider a new class of analytic functions in the unit disk using polynomials of order alpha. we give some sufficient conditions for functions belonging to this class.

In this paper‎, ‎we introduce a new class$T_{k}^{s,a}[A,B,alpha‎ ,‎beta ]$ of analytic functions by using a‎ ‎newly defined convolution operator‎. ‎This class contains many known classes of‎ ‎analytic and univalent functions as special cases‎. ‎We derived some‎ ‎interesting results including inclusion relationships‎, ‎a radius problem and‎ ‎sharp coefficient bound for this class‎.

The urokinase-type plasminogen activator (uPA) interacts with its receptor (uPAR) to promote local proteolysis as well as cellular proliferation and migration. These functions contribute to the pathogenesis of lung inflammation and remodeling as well as the growth and invasiveness of lung neoplasms. In this study, we sought to determine if uPA alters its own expression in lung epithelial cells....