To test the hypothesis that the electrocardiogram of cardiac rupture is due to acute cardiac tamponade, 27 episodes of cardiac tamponade were produced in ten open-chest dogs. During continuous monitoring of the electrocardiogram and the arterial and venous pressures, 10-30 cc of autologous, heparinized blood, or one of several other solutions, were intermittently infused into the pericardial sa...

A persistent problem in estimating the severity of local tsunamis generated by earthquakes is explaining the great event-to-event variability of tsunami run-up heights relative to the magnitude of the earthquake. Undoubtedly, there is always variability in run-up that is dependent on local bathymetry. However, many earthquakes in recent years have produced unexpectedly high local run-up heights...

We extend the McPherson Model for silicon-oxygen bond-breakage derived for a single SiO4 tetrahedron to capture the influence of the whole lattice. Several pair-wise potentials have been compared in the model including Mie-Grüneisen as well as diverse forms of TTAM/BKS. The contribution of the whole lattice substantially increases the activation energy for the Si-O bond rupture. The correspondi...

Viruses are biological agents with great potential in the field of nanotechnology. Nowadays, their amazing properties are starting to be unveiled using physical techniques like the atomic force microscope. In this study, we have used a Virtual AFM, i.e., a simulator that mimics a typical AFM nanoindentation experiment, to study the mechanical properties of viral shells. In particular, with our ...

This study presents a numerical investigation of the source aspect ratio (AR) influence on tsunami decay characteristics with an emphasis in near and far-field differences for two initial wave shapes Pure Positive Wave N-wave. It is shown that, when total energy both types kept same, short-rupture more concentrated are likely to be destructive near-field, whereas long rupture dangerous far-fiel...

We present a simulation method to assess the quasistatic fracture resistance of materials. Set within semi-grand-canonical Monte Carlo (SGCMC) environment, an auxiliary field---the bond rupture potential---is introduced generate sufficiently large number possible microstates in ensemble, and associated energy fluctuations. The SGCMC approach permits identifying full phase diagram brittle for ha...

Cell adhesion complexes (CACs), which are activated by ligand binding, play key roles in many cellular functions ranging from cell cycle regulation to mediation of cell extracellular matrix adhesion. Inspired by single molecule pulling experiments using atomic force spectroscopy on leukocyte function-associated antigen-1 (LFA-1), expressed in T-cells, bound to intercellular adhesion molecules (...

The issue of spontaneous ignition of highly pressurized hydrogen release is of important safety concern, e.g. in the assessment of safety risk and design of safety measures. This paper reports on recent numerical investigation of this phenomenon through releases via a tube using a 5-order WENO scheme. A mixture-averaged multi-component approach was used for accurate calculation of molecular tra...