نتایج جستجو برای: running wheel exercise

تعداد نتایج: 261182  

2013
Iván J. Santos-Soto Nataliya Chorna Néstor M. Carballeira José G. Vélez-Bartolomei Ana T. Méndez-Merced Anatoliy P. Chornyy Sandra Peña de Ortiz

Combinatorial therapies using voluntary exercise and diet supplementation with polyunsaturated fatty acids have synergistic effects benefiting brain function and behavior. Here, we assessed the effects of voluntary exercise on anxiety-like behavior and on total FA accumulation within three brain regions: cortex, hippocampus, and cerebellum of running versus sedentary young adult male C57/BL6J m...

Journal: :Journal of applied physiology 2001
C P Avula A R Muthukumar K Zaman R McCarter G Fernandes

Two-month-old mice were placed in cages with (Ex) or without exercise running wheels with free access to the wheel 24 h/day for 10 mo. An equal amount of food for both groups was provided daily. Ex mice ran an average of 33.67 km/wk initially, and exercise decreased gradually with age. Ex mice had gained an average of 43.5% less body weight at the end of the experiment. Although serum lipid per...

Journal: :Physiological genomics 2010
Scott A Kelly Derrick L Nehrenberg Jeremy L Peirce Kunjie Hua Brian M Steffy Tim Wiltshire Fernando Pardo-Manuel de Villena Theodore Garland Daniel Pomp

Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects of quantitative trait loci (QTL) controlling genetic predisposition for exercise-related traits, utilizing a large advanced intercross line (AIL) of mice. This AIL (G(4)) population originated f...

2017
Rolf Schreckenberg Anja-Maria Horn Rui M. da Costa Rebelo Sakine Simsekyilmaz Bernd Niemann Ling Li Susanne Rohrbach Klaus-Dieter Schlüter

Purpose: According to the current therapeutic guidelines of the WHO physical activity and exercise are recommended as first-line therapy of arterial hypertension. Previous results lead to the conclusion, however, that hearts of spontaneously hypertensive rats (SHR) with established hypertension cannot compensate for the haemodynamic stresses caused by long-term exercise. The current study was i...

2016
Danilo E. F. L. Flôres Crystal N. Bettilyon Lori Jia Shin Yamazaki

Rodents anticipate rewarding stimuli such as daily meals, mates, and stimulant drugs. When a single meal is provided daily at a fixed time of day, an increase in activity, known as food anticipatory activity (FAA), occurs several hours before feeding time. The factors affecting the expression of FAA have not been well-studied. Understanding these factors may provide clues to the undiscovered an...

Journal: :American journal of physiology. Endocrinology and metabolism 2012
Lindsay G Carter Kaitlyn N Lewis Donald C Wilkerson Christine M Tobia Sara Y Ngo Tenlep Preetha Shridas Mary L Garcia-Cazarin Gretchen Wolff Francisco H Andrade Richard J Charnigo Karyn A Esser Josephine M Egan Rafael de Cabo Kevin J Pearson

Emerging research has shown that subtle factors during pregnancy and gestation can influence long-term health in offspring. In an attempt to be proactive, we set out to explore whether a nonpharmacological intervention, perinatal exercise, might improve offspring health. Female mice were separated into sedentary or exercise cohorts, with the exercise cohort having voluntary access to a running ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Friederike Klempin Daniel Beis Valentina Mosienko Gerd Kempermann Michael Bader Natalia Alenina

Voluntary wheel running has long been known to induce precursor cell proliferation in adult hippocampal neurogenesis in rodents. However, mechanisms that couple activity with the promitotic effect are not yet fully understood. Using tryptophan hydroxylase (TPH) 2 deficient (Tph2-deficient) mice that lack brain serotonin, we explored the relationship between serotonin signaling and exercise-indu...

Journal: :Proceedings of the Royal Society B: Biological Sciences 2014

Journal: :Neuroscience 2015
C P Hutton N Déry E Rosa J A Lemon C D Rollo D R Boreham M Fahnestock D deCatanzaro J M Wojtowicz S Becker

Severe chronic stress can have a profoundly negative impact on the brain, affecting plasticity, neurogenesis, memory and mood. On the other hand, there are factors that upregulate neurogenesis, which include dietary antioxidants and physical activity. These factors are associated with biochemical processes that are also altered in age-related cognitive decline and dementia, such as neurotrophin...

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