Background: Euphorbia plants are traditionally used in folk medicine for infections, inflammation, and cancer. Objectives: To investigate the effects of the butanolic extracts of Euphorbia micorociadia and Euphorbia osyridea on specific transcription factors and cytokines expression of T cell subsets. Methods: Activated mouse splenocytes were cultured in the presence of non-cytotoxic concentrat...

Background Multiple sclerosis (MS) is a chronic autoimmune disease. Ellagic acid natural polyphenol and affects the fate of neurons through its anti-inflammatory antioxidant properties. The present study aimed to investigate ellagic effects on disease severity, expression involved genes in pathogenesis MS, levels related cytokines. Methods was triple-blind clinical trial. Eligible patients were...