نتایج جستجو برای: rna protecting role

تعداد نتایج: 1482019  

Journal: :FEBS Letters 2021

In this report, using the database of RNA-binding protein specificities (RBPDB) and our previously published RNA-seq data, we analyzed interactions between RNA proteins to decipher role alternative splicing in metabolic disorders induced by TNF-α. We identified 13 395 unique RNA–RBP interactions, including 385 motifs 35 RBPs, some which (including MBNL-1 3, ZFP36, ZRANB2, SNRPA) are transcripti...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده زبانهای خارجی 1393

the purpose of this study was to examine the comparative effect of story retelling and role playing on efl learners’ vocabulary learning and reading comprehension. to carry out the purpose of the study 90 female learners of tabarestan language school located in noshahr were non-randomly selected. they took pet test and among these 90 participants 62 students were selected as homogenous learners...

2013
Ekaterina R Kim Anastasia A Selyutina Ilya A Buldakov Valentina Evdokimova Lev P Ovchinnikov Alexey V Sorokin

The Y-box binding protein 1 (YB-1) is a DNA/RNA-binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA and RNA-dependent events is determined by its localization in the cell. We have shown previously that YB-1 is cleaved by 20S proteasome between E219 and G220, and the truncated N-terminal YB-1 fragment accumulates in the nuclei of cells treated with DNA damaging drugs....

2012
Zbigniew Darzynkiewicz Endre A. Balazs

Faithful preservation of genome integrity is the critical mission of stem cells as well as of germ cells. Reviewed are the following mechanisms involved in protecting DNA in these cells: (a) The efflux machinery that can pump out variety of genotoxins in ATP-dependent manner; (b) the mechanisms maintaining minimal metabolic activity which reduces generation of reactive oxidants, by-products of ...

2017
Guangyuan Zhao Cheng Fu Lu Wang Lan Zhu Yutao Yan Ying Xiang Fang Zheng Feili Gong Song Chen Gang Chen

Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion injury (IRI), highlighting a role for intracellular HMGB1 in cellular protection. Down-regulation of nuclear HMGB1 by small interfering RNA (siRNA) might not only decrease its injurious extracellular role by reducing its release but also serve to maintain its beneficial intracel...

2013
Helena J. Maier Philippa C. Hawes Eleanor M. Cottam Judith Mantell Paul Verkade Paul Monaghan Tom Wileman Paul Britton

UNLABELLED Replication of positive-sense RNA viruses is associated with the rearrangement of cellular membranes. Previous work on the infection of tissue culture cell lines with the betacoronaviruses mouse hepatitis virus and severe acute respiratory syndrome coronavirus (SARS-CoV) showed that they generate double-membrane vesicles (DMVs) and convoluted membranes as part of a reticular membrane...

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