نتایج جستجو برای: riz

تعداد نتایج: 349  

Journal: :Haematologica 2014
Julie Damgaard Sandahl Eva A Coenen Erik Forestier Jochen Harbott Bertil Johansson Gitte Kerndrup Souichi Adachi Anne Auvrignon H Berna Beverloo Jean-Michel Cayuela Lucy Chilton Maarten Fornerod Valérie de Haas Christine J Harrison Hiroto Inaba Gertjan J L Kaspers Der-Cherng Liang Franco Locatelli Riccardo Masetti Christine Perot Susana C Raimondi Katarina Reinhardt Daisuke Tomizawa Nils von Neuhoff Marco Zecca C Michel Zwaan Marry M van den Heuvel-Eibrink Henrik Hasle

Acute myeloid leukemia with t(6;9)(p22;q34) is listed as a distinct entity in the 2008 World Health Organization classification, but little is known about the clinical implications of t(6;9)-positive myeloid leukemia in children. This international multicenter study presents the clinical and genetic characteristics of 62 pediatric patients with t(6;9)/DEK-NUP214-rearranged myeloid leukemia; 54 ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Ulrich Lehmann Ina Berg-Ribbe Luzie U Wingen Kai Brakensiek Thomas Becker Jürgen Klempnauer Brigitte Schlegelberger Hans Kreipe Peer Flemming

PURPOSE A comparative quantitative methylation profiling of hepatocellular carcinoma and the most frequent benign liver tumor, hepatocellular adenoma, was set up for the identification of tumor-specific methylation patterns. EXPERIMENTAL DESIGN The quantitative methylation levels of nine genes (RASSF1A, cyclinD2, p16INK4a, DAP-K, APC, RIZ-1, HIN-1, GSTpi1, SOCS-1) were analyzed in hepatocellu...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Cynthia C Jung Denize Atan David Ng Lynda Ploder Sarah E Ross Martin Klein David G Birch Eduardo Diez Roderick R McInnes

Retinal bipolar (BP) cells mediate the earliest steps in image processing in the visual system, but the genetic pathways that regulate their development and function are incompletely known. We identified PRDI-BF1 and RIZ homology domain containing 8 (PRDM8) as a highly conserved transcription factor that is abundantly expressed in mouse retina. During development and in maturity, PRDM8 is expre...

Journal: :Chinese medical journal 2015
Hong-Xia Bi Han-Bing Shi Ting Zhang Ge Cui

BACKGROUND As a novel molecular markerof non-small cell lung cancer (NSCLC), PRDI-BF1 and RIZ homology domain containing protein 14 (PRDM14) is over-expressed in NSCLC tumor tissues. Extracellular matrix degradation mediated by the balance between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) is one of the most important mechanism in lung cancer metastasis....

2017
A. Neshasteh-Riz S. Babaloui S. Khoei

*Corresponding author: Dr. Ali Neshasteh Riz, Department of Radiology, Iran University of Medical Sciences, P.O. Box: 14155-6183, Tehran, Iran. Fax: + 98 21 88054355 Email: [email protected] Background: Glioblastoma is the most common and most malignant cancer of central nervous system. Targeted radiotherapy is an effective method toward its treatment. Iododeoxyuridine (IUdR) is a halogena...

2016
Lei Wang Qiong‐Qiong Ding Shan‐Shan Gao Hai‐Jie Yang Mian Wang Yu Shi Bin‐Feng Cheng Jia‐Jia Bi Zhi‐Wei Feng

PRDM (PRDI-BF1 and RIZ domain-containing) proteins constitute a family of zinc finger proteins and play important roles in multiple cellular processes by acting as epigenetic modifiers. PRDM5 is a recently identified member of the PRDM family and may function as a tumor suppressor in several types of cancer. However, the role of PRDM5 in murine melanoma remains largely unknown. In our study, ef...

2014
K. Mihara S. Kagawa T. Suzuki T. Kondo

▼ Introduction: The eff ects of escitalopram (10 mg/d) coadministration on plasma concentrations of aripiprazole and its active metabolite, dehydroaripiprazole, were studied in 13 Japanese psychiatric patients and compared with those of paroxetine (10 mg/d) coadministration. Methods: The patients had received 6–24 mg/d of aripiprazole for at least 2 weeks. Patients were randomly allocated to on...

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