BACKGROUND Autoimmune hemolytic anemia (AIHA) is a less recognized, potentially fatal condition. There is a scarcity of data on clinicoserological characteristics and response to therapy concerning this disease from South India. METHODS Data for 33 patients with primary AIHA recorded from July 2009 to June 2015 were retrospectively analyzed for clinical presentation, response to frontline the...

By ROBERT SCHWARTZ AND WILLIAM DAMESHEK P RIOR TO 1949, the treatment of autoimmune hemolytic anemia ( AIHA) was frequently disappointing. Despite splenectomy and the use of blood transfusions, many patients had an unremitting and progressively deteriorating course which ended fatally. With the introduction of ACTH and cortisone, the treatment of this disorder was greatly facilitated and benefi...

Objectives We studied the involvement of serum-complement (C') and oxidative stress in the hemolytic anemias Paroxysmal Nocturnal Hemoglobinuria (PNH) and Auto-Immune Hemolytic Anemia (AIHA), and the effect of Fermented Papaya Preparation (FPP), an antioxidant-containing yeast fermentation product of Carica papaya Linn. Methodology Normal human red blood cells (RBC) treated with the sulphydryl ...

RATIONALE We report a complicated case of cholestatic hepatitis with suspected autoimmune hemolytic anemia (AIHA) and copper toxicity syndrome after HSCT and donor lymphocyte infusion (DLI). PATIENT CONCERNS A 19-year-1-month-old girl presented with a history of CML. She underwent matched unrelated donor HSCT and donor lymphocyte infusion subsequently. Three months later, yellowish discolorat...

INTRODUCTION Distributing daily protein intake evenly across meals (∼25-30g/meal) has been suggested to improve muscle mass. The aim of this research is to examine the association between grip strength, total protein intake and its distribution across day's meals in older adults. METHODS Nationally representative dietary intake data of adults aged 51 years and older (n = 4,123) who participat...

post spinal puncture headache (psph) is a well known complication of spinal anesthesia. it occurs after spinal anesthesia induction due to dural and arachnoid puncture and has a significant effect on the patient’s postoperative well being. this manuscript is based on an observational study that runs on babol university of medical sciences and review of literatures about current concepts about t...

CLL has been defined as presence of more than 5000 small mature appearing monoclonal B lymphocytes with a specific immunophenotype in peripheral blood. It is a well-known fact that CLL is associated with autoimmune cytopenias. CLL cells are CD5(+) B lymphocytes, and usually are not the "guilty" cells which produce autoantibodies. T cell defect is another characteristic of CLL and the total numb...

Present study reveals the effects of microcystin-LR (2.5 μg/25g bw) toxins on certain biochemical parameters in blood of H. fossilis. In treated fish serum bilirubin, serum cholesterol, serum creatinine and serum urea levels are increased. Serum protein content of treated fish is decreased. Present study suggests that MCLR is toxic to fresh water catfish Heteropneustes fossilis.