Background Summary: To examine the relationship between cardiovascular magnetic resonance imaging (CMR) parameters and pregnancy outcomes post Mustard palliation. Background: Impaired systemic ventricular function and presence of a systemic right ventricle (RV) are associated with adverse events in pregnancy. Women with transposition of the great arteries post atrial switch (Mustard procedure) ...

an elevated pulmonary artery pressure (pap) from any cause is associated with increased mortality, especially in cases of primary pulmonary arterial hypertension (pah). one of the many reasons behind a bad prognosis is the inherent difficulty in assessing right ventricular (rv) function with reproducible methods. intensive research involving the left heart has made it relatively easy to assess ...

Background. The right ventricle (RV) receives part of its systolic pumping force from the left ventricle through systolic ventricular interaction. The purpose of this study was to determine the effects of dilated cardiomyopathy on left ventricular to right ventricular (LV-to-RV) systolic interaction. Methods and Results. Studies were performed in six normal pigs and in six pigs in which dilated...

The role of the left ventricle in ICU patients with circulatory shock has long been considered. However, acute right ventricle (RV) dysfunction causes and aggravates many common critical diseases (acute respiratory distress syndrome, pulmonary embolism, acute myocardial infarction, and postoperative cardiac surgery). Several supportive therapies, including mechanical ventilation and fluid manag...

BACKGROUND The right ventricular (RV) dyssynchrony has not been studied extensively and the existing literature has established the effect of cardiac resynchronization therapy (CRT) on the left ventricular (LV) dyssynchrony, but there is a dearth of data on the effect of CRT on the forgotten ventricle. We sought to evaluate the presence of mechanical right ventricular dyssynchrony in patients w...

BACKGROUND Right ventricular dysfunction in COPD is common, even in the absence of pulmonary hypertension. The aim of the present study was to examine the effects of high intensity interval training (HIIT) on right ventricular (RV) function, as well as pulmonary blood vessel remodeling in a mouse model of COPD. METHODS 42 female A/JOlaHsd mice were randomized to exposure to either cigarette s...

Persistent pulmonary hypertension of the newborn (PPHN) results in right ventricular (RV) hypertrophy followed by right heart failure and an associated mitochondrial dysfunction. The phospholipid cardiolipin plays a key role in maintaining mitochondrial respiratory and cardiac function via modulation of the activities of enzymes involved in oxidative phosphorylation. In this study, changes in c...

Studies about pulmonary hypertension and congenital heart diseases have introduced the concept of right ventricular remodeling leading these pathologies to a similar outcome: right ventricular failure. However right ventricular remodeling is also a physiological process that enables the normal fetal right ventricle to adapt at birth and gain its adult phenotype. The healthy mature right ventric...

The right ventricle (RV) of the heart is responsible for pumping blood to the lungs. Its kinematics are not as well understood as that of the left ventricle (LV) due to its thin wall and asymmetric geometry. In this study, the combination of tagged MRI and three-dimensional (3-D) image-processing techniques was used to reconstruct 3-D RV-LV motion and deformation. The reconstructed models were ...

The management of patients with acute respiratory distress syndrome (ARDS) has deeply changed in recent years. While the ventilatory strategy was initially focused on the lung, now it also considers pulmonary vascular injury and its effects on the right ventricle and on hemodynamics. This is mainly due to echocardiography, which allows intensivists to evaluate accurately, non invasively and at ...