N-methyl-D-aspartate receptors (NMDARs), a major subtype of glutamate receptors mediating excitatory transmission throughout the central nervous system (CNS), play critical roles in governing brain function and cognition. Because NMDAR dysfunction contributes to the etiology of neurological and psychiatric disorders including stroke and schizophrenia, NMDAR modulators are potential drug candida...

This paper aims to establish two bijections: from regions of the r -Shi arrangement O -rooted labeled -trees, and -Catalan pairings permutation -Dyck path. To this end, we introduce a cubic matrix for each region hyperplane arrangements. The first bijection is established by reading positions minimal positive entries in its column slices. second one obtained numbers slice, which turns out be es...

Machine learning models fit complex algorithms to arbitrarily large datasets. These are well known be high on performance and low interpretability. We use interactive visualization of slices predictor space address the interpretability deficit; in effect opening up black-box machine algorithms, for purpose interrogating, explaining, validating comparing model fits. Slices specified directly thr...

Norepinephrine (NE) and glutamate (Glu) initiate intracellular calcium ([Ca2+]i) transients, oscillations, and intracellular [Ca2+]i waves in cultured astrocytes. To further elucidate the significance of NE- and Glu-evoked astrocytic [Ca2+]i signaling to neuron-astrocyte communication in the mature CNS, [Ca2+]i of astrocyte networks within hippocampal slices (P21-42) was measured during bath ap...

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