Structural modifications of AOT/water/isooctane reverse micelles due to incorporation of proteins were studied at various water contents and protein concentrations, using small-angle X-ray scattering (SAXS) experiments under static conditions, rheometry analysis, and SR-SAXS experiments under induced shear flow. Two proteins, lysozyme (pI 11.1, Mw 14,300 Da) and BSA (pI 4.3, Mw 66,700 Da), were...

The objective of our work was to study the micromeritic properties of lyophilized diclofenac potassium-loaded lipospheres and to evaluate in vivo, the analgesic properties of diclofenac potassium in the lipospheres in addition to other in vitro properties. Solidified reverse micellar solutions were prepared by fusion using 1:1, 2:1, and 1:2% w/w of Phospholipon(®) 90H and Softisan(®) 154. Diclo...

Background A high resolution real-time phase-contrast MRI flow technique was used to measure flow dynamics in the ascending aorta as well as superior vena cava. MRI technique based on undersampled radial fast low-angle shot acquisitions with phase-sensitive image reconstructions by regularized nonlinear inversion. Normal flow values as well as flow measurements during physiologic stress tests l...

The increasing demands for highly performant, proven correct, easily maintainable, extensible programs together with the continuous growth of real-world programs strengthen the pressure for powerful and scalable program analyses for program development and code generation. Multi-core computing systems offer new chances for enhancing the scalability of program analyses, if the additional computi...

Manufacturers and their distributors must cope with an increased flow of returned products from their customers. The value of commercial product returns, which we define as products returned for any reason within 90 days of sale, now exceeds US $100 billion annually in the US. Although the reverse supply chain of returned products represents a sizeable flow of potentially recoverable assets, on...