Rev is the regulatory protein for the replication of HIV-1. Rev (11-20) peptide is known as an indispensable region regarding the function of the nuclear entry inhibitory signal of Rev. In this study, the antifungal effects of Rev (11-20) peptide were investigated. Rev (11-20) peptide had potent fungicidalactivities without cytotoxicity. To understand the target site(s) of Rev (11-20) peptide, ...

Discussion in the Efficacy Working Party (EWP) June/October 1996 February 1997 Transmission to the CPMP March 1997 Transmission to interested parties March 1997 Deadline for comments September 1997 Re-submission to the EWP December 1997 Approval by the CPMP December 1997 Date for coming into operation June 1998 Draft Rev. 1 Agreed by the EWP April 2010 Adoption Rev. 1 by CHMP for release for co...

HIV-1 Rev is an ~13 kD accessory protein expressed during the early stage of virus replication. After translation, Rev enters the nucleus and binds the Rev response element (RRE), a ~350 nucleotide, highly structured element embedded in the env gene in unspliced and singly spliced viral RNA transcripts. Rev-RNA assemblies subsequently recruit Crm1 and other cellular proteins to form larger comp...

The HIV-1 Rev protein activates nuclear export of unspliced and partially spliced viral RNA transcripts, which encode the viral genome and the genes encoding viral structural proteins, by binding to and oligomerizing on the Rev Response Element (RRE). The human DEAD-box protein 1 (DDX1) enhances the RNA export activity of Rev through an unknown mechanism. Using a single-molecule assembly assay ...

Publications in refereed journals 1 Observation of e+e− annihilations into the C = +1 hadronic final states ρρ and φρ B. Aubert et al. [BABAR Collaboration], Phys. Rev. Lett. 97, 112002 (2006). 2 Search for the decay B → K SK SK L B. Aubert et al. [BABAR Collaboration], Phys. Rev. D 74, 032005 (2006). 3 Search for doubly charmed baryons Ξcc and Ξ ++ cc in BABAR B. Aubert et al. [BABAR Collabora...

to s,Trio+'4'(y, )4'(y,)]. The expansion of the operator product contains terms proportional to the scalar gluon field y(x) such as Iyi y-. l' "'~ "+'s (y, y-.)ly, -y, l 'J''«~(~)8 (o, y„~y, +(&-~)y, ). This quark-antiquark singularity leads to a term in 6'(x, k) that falls off as 6'„(x,k) ~ Ikl' '"" ' ~ ' = Ikl '. R. Blankenbecler, Phys. Rev. D 8, 287 (1978); S. J. Brodsky, F. E. Close, and J....