Longitudinal data were analysed on the lung function of 25 of 29 survivors of childhood leukaemia or lymphoma, who had been conditioned with cyclophosphamide and total body irradiation before allogeneic bone marrow transplantation, to test whether children are particularly vulnerable to pulmonary damage after transplantation. None developed chronic graft-versus-host disease. Transfer factor and...

Pulmonary function tests (PFT) are a battery of tests that measure lung function and aid in the management of patients with respiratory disease. They are performed using standardized equipment and can be used for diagnosis, prognostication, management and follow-up of patients with pulmonary pathology. Although PFT may not identify the exact pathology, it broadly classifies respiratory disorder...

Respiratory tract involvement is common in adults with systemic lupus erythematosus (SLE). Although SLE in children usually follows a more severe course than in adults, there are few reports on pulmonary disease and lung function in children with SLE. We performed lung function tests and chest x ray examinations in eight children with SLE (mean age 11.1 years), three of whom presented with pulm...

Background: Chronic Obstructive Pulmonary Disease (COPD) is a primary lung disease but as it advances, there is restriction in chest wall mobility which decreases pulmonary functions and vital capacity of lung. So purpose of this study is to assess the immediate effect of Chest Mobilization (CM) on improving the Chest Expansion (CE). Objective Of Study: To improve Chest Expansion in patients of...

Himalayan P-waves (amplitude > 5 mm) are often known to be classically associated with congenital heart diseases with right to left shunt like tricuspid atresia, Ebstein anomaly, combined tricuspid and pulmonic stenosis, ischemic heart disease, restrictive cardiomyopathy, etc., where they indicate a dilated right atrium and tend to be persistent. This type of P-waves is rarely seen in long-stan...

OBJECTIVE Occupational exposure to silica dust is associated with significant impairment of lung function. The present study investigates which pathological changes in the lung are associated with impairment of lung function in silica dust exposed workers who were life-long non-smokers. METHODS 242 South African white gold miners who were lifelong non-smokers and who had a necropsy at death w...

Emerging evidence indicates that nonalcoholic fatty liver disease (NAFLD) is associated with a wide variety of extrahepatic complications. However, the potential association between impaired pulmonary function and NAFLD has been less investigated. This study examined the relationship between pulmonary function and hepatic steatosis in 9976 adults participating in a cross-sectional analysis of t...

Few therapies exist for the relief of dyspnea in restrictive lung disorders. Accumulating evidence suggests that nebulized opioids selective for the mu-receptor subtype may relieve dyspnea by modulating intrapulmonary opioid receptor activity. Our respective primary and secondary objectives were to test the hypothesis that nebulized fentanyl (a mu-opioid receptor agonist) relieves dyspnea durin...