While damping devices can provide supplemental to mitigate building vibration due wind or earthquake effects, integrating them into the design is more complex. For example, Canadian code does not designs with inline friction dampers. The objective of this present article was study overstrength, ductility, and response modification factors concrete frame buildings dampers in context. that purpos...

objective: antisocial, aggressive and delinquent behaviors in adults often begin early in life. basal cortisol is a valuable biological marker in children with disruptive behavior disorder (dbd). to investigate the association between biological factor (cortisol) and disruptive behaviors, we studied the effect of family training on salivary cortisol level in children with dbd. methods: basal sa...

Active immunotherapy for lung cancer has been a challenge because of the poor antigenic characterization of these tumors and their ability to escape the immune response. However, knowledge of the mechanisms of anti-tumor immunity has expanded significantly over the past decade, leading to the development of more novel, specific strategies for augmenting the immune response. Genetic manipulation...

In this work, we report on the synthesis of superparamagnetic iron oxide nanoparticles at room temperature using microemulsion template phase consisting of cyclohexane, water, CTAB as cationic surfactant and butanol as a cosurfactant. Surface modification have been carried out by using poly(ethyleneglycol) (PEG). The structure,morphology, and magnetic properties of the products were characteriz...

1. Modification with 2,4,6-trinitrobenzenesulphonic acid was studied for its effect on the structure, activity and response to regulatory effectors of ox liver glutamate dehydrogenase. 2. The modification affected amino groups only, and the relative reactivities of the amino groups of the enzyme are described. 3. A biphasic inactivation of the enzyme was observed and analysis of the course of i...

current mainstay of treatment for human immunodeficiency virus (hiv)-infected patients is highly active antiretroviral therapy (haart) but little is known about the long-term clinical outcome for hiv-infected patients who have received haart. determining factors associated with longterm survival in the course of treatment may allow modification to be made for patients who are at a greater risk ...

The number of factors known to participate in the DNA damage response (DDR) has expanded considerably in recent years to include splicing and alternative splicing factors. While the binding of splicing proteins and ribonucleoprotein complexes to nascent transcripts prevents genomic instability by deterring the formation of RNA/DNA duplexes, splicing factors are also recruited to, or removed fro...

Sterile attenuation of Plasmodium parasites at the liver-stage either by irradiation or genetic modification, or at the blood-stage by chemoprophylaxis, has been shown to induce immune responses that can protect against subsequent wild-type infection. However, following certain interventions, parasite attenuation can be incomplete or non-sterile. Instead parasites are rendered developmentally s...

Regulatory T cells (Tregs) are an important subset of adaptive immune cells and control immune reactions for maintaining homeostasis. Tregs are generated upon their encounter with self or non-self-antigen and mediate tolerance or suppress aberrant immune responses. A high level of specificity of Tregs to recognize antigen(s) suggested their instrumental potential to treat various inflammatory d...