Aortopulmonary pressure difference and pulmonary blood flow velocity were studied during the first 48 hours of life in 12 premature neonates with severe respiratory distress syndrome (RDS), treated by natural surfactant, and in 25 premature neonates with mild RDS. A non-invasive Doppler ultrasound method was used to estimate aortopulmonary pressure difference and pulmonary blood flow velocity f...

background and objective: preterm birth is a public health problem and late preterm birth (deliveries between 34-36 weeks of gestation) accounts for 75% of all preterm births. antenatal betamethasone can reduce the severity of respiratory distress in preterm infants and its effect is accepted in 24-34 weeks of gestation. our goal was to determine the neonatal outcomes of betamethasone prescript...

background: pyrethroids are generally of low toxicity to humans, but in suicidal poisonings which are usually associated with ingestion of high doses, they lead to severe systemic effects. case report: a 30-year old woman presented to emergency department with a history of intentional ingestion of about 15 ml of prallethrin around 3 days earlier. she complained of shortness of breath along with...

background: various strategies have been suggested for the treatment of respiratory distress syndrome (rds). objectives: the aim of this study was to compare the efficacies of two common methods of rds management among neonates with low birth weight. patients and methods: a cohort study was conducted on 98 neonates with definite diagnosis of rds during 2008-2009. the neonates were divided into ...

Increasing evidence has demonstrated that lung fluid absorption disorders might be an important cause of neonatal respiratory distress syndrome (RDS) by influencing gas exchange or surfactant function. The SCNN1A gene, which encodes the α-ENaC, might predispose infants to RDS. To explore whether the single-nucleotide polymorphisms (SNPs) of SCNN1A are associated with RDS, we conducted a case-co...

Background: Respiratory distress syndrome (RDS) is a major cause of neonatal morbidity and mortality, affecting approximately 1% all live births 10% preterm infants. Lamellar bodies represent storage form pulmonary surfactant within Type II pneumocytes, secretion which increases with advancing gestational age, thus enabling prediction the degree FLM. Preterm premature rupture membranes (PPROM) ...

OBJECTIVE To explore birth rate, delivery mode, medical problems, requirement of respiratory support, and acute outcomes of late preterm infants in Zhejiang province in eastern China. METHODS Eleven tertiary hospitals were recruited. Clinical data of every nursery admission from January to December 2007 were collected and analyzed. RESULTS During the study period, 44,362 infants were born w...

Pulmonary function in a normal fetus is dependent upon maturation and maintenance of the biochemical synthesis of a distinct surface-active lipid. Two major pathways for the biosynthesis of this major surface-active lipid, dipalmitoyl lecithin, are described and relative activities of each pathway in human lung are discussed. In normal human lung, the CDP-choline path­ way is quantitatively mos...

Fetal lung maturity assessment in twin pregnancy has been discussed, but is still controversial. The purpose of this study is to predict the occurrence of respiratory distress syndrome (RDS) using lamellar body count (LBC) and analyze the validity of LBC for fetal lung maturity assessment in twin pregnancy. Three-hundred two amniotic fluid samples were obtained at cesarean section from 29 to 38...