Background: Advanced gastric cancer (AGC) causes a huge economic burden to the society. This openlabel study was conducted to compare the efficacy and acceptability of oxaliplatin plus tegafur (OXT) vs. oxaliplatin plus S-1 (OXS) for chemotherapy-naive advanced gastric cancer patients. Material and methods: In this study, patients were randomly assigned to receive OXT or OXS. In a 3-week treatm...

γ-Amino butyric acid (GABA) plays a key role in the regulation of central nervous system by activating synaptic and extrasynaptic GABAA receptors. It is acknowledged that extrasynaptic GABAA receptors located in the soma, dendrites, and axons may be activated tonically by low extracellular GABA concentrations. The activation of these receptors produces a persistent conductance that can hyperpol...

Reverberation, especially in large rooms, severely degrades speech recognition performance and speech intelligibility. Since direct measurement of room characteristics is usually not possible, blind estimation of reverberation-related metrics such as the reverberation time (RT) and the direct-to-reverberant energy ratio (DRR) can be valuable information to speech recognition and enhancement alg...

In this paper, we evaluate the performance of Deficit Round Robin Fair Queuing applied in router congestion control. Two parameters affect the performance of a DRR router: the number of flows and the buffer size. We study the influence of the two parameters on fairness. The results show that the optimal region can be achieved by means of one-dimensional optimization. Then, we investigate the im...

One of the main applications for computers in medicine is to digitally merge patient data that originates from different sources. For our 2D-3D Registration problem, this means finding the right spatial alignment of a three-dimensional Computed Tomography (CT) data set and one or two X-Ray images from the same patient. An automatic algorithm has to create a digitally reconstructed radiograph (D...

Bone tracking from X-Ray sequences is important for biological and evolutionary applications like motion analysis of species, and also in human health, for example in surgical guidance, study of kinematics, or post-operative implant assessment. Since X-Ray data is 2-dimensional, it does not provide enough information about the 3D position of the bones. C-Arm technology (Fig. 1) reduces this pro...

The Sendai Framework for Disaster Risk Reduction 2015–2030 (SFDRR) is the guiding international policy structure disaster risk reduction activities, shaping DRR strategies and practices across world. Its targets, priorities, supporting documents are critical in influencing direction of programming funding streams national local level interventions, its indicators play a vital role setting bench...

Motivated by applications to modern networking technologies, there has been interest in designing efficient gossip-based protocols for computing aggregate functions. While gossip-based protocols provide robustness due to their randomized nature, reducing the message and time complexity of these protocols is also of paramount importance in the context of resource-constrained networks such as sen...

Purpose As stated in the United Nations Global Assessment Report 2022 Concept Note, decision-makers everywhere need data and statistics that are accurate, timely, sufficiently disaggregated, relevant, accessible easy to use. The purpose of this paper is demonstrate scalable replicable methods advance integrate use earth observation (EO), specifically ongoing efforts within Group on Earth Observ...

Purpose The plethora of contributions to social learning has resulted in a wide range interpretations, meanings and applications learning, both within across disciplines. However, advancing the concept using methods tools areas like disaster-shocks requires interdisciplinary consolidation understandings. In this context, primary focus paper is on disaster risk reduction (DRR). Design/methodolog...