introduction: conventional methods for diagnosis of external root resorption (err) are based on clinical findings and x-ray observations which are not appropriate for early diagnosis. the present study assessed the effect of different sizes and field of views (fovs) in the diagnosis of simulated external root resorption by cone-beam computed tomography (cbct). methods and materials: in this dia...

external inflammatory root resorption (eir) represents a challenge in endodontic practice. eir commonly occurs after dental trauma that results in periodontal ligament injury, pulp necrosis and subsequent infection.  treatment of eir is based on disinfecting the root canal system through chemomechanical procedures and then filling it with calcium hydroxide or triple antibiotic paste. dental tra...

In this issue of Cell, McDonald et al. show that giant multinucleated, bone-resorbing osteoclasts dissolve into smaller cells, termed “osteopmorhs,” which re-form at distal bone sites (McDonald al., 2021McDonald M.M. Khoo W.H. Ng P.Y. Xiao Y. Zamerli J. Thatcher P. Kyaw W. Pathmanandavel K. Grootveld A.K. Moran I. al.Osteoclasts recycle via osteomorphs during RANKL-stimulated resorption.Cell. 2...

In this paper we develop a lattice-based computational model focused on bone resorption by osteoclasts in a single cortical basic multicellular unit (BMU). Our model takes into account the interaction of osteoclasts with the bone matrix, the interaction of osteoclasts with each other, the generation of osteoclasts from a growing blood vessel, and the renewal of osteoclast nuclei by cell fusion....

The aim of this study is to present a classification with a clinical application for root resorption, so that diagnosis will be more objective and immediately linked to the source of the problem, leading the clinician to automatically develop the likely treatment plan with a precise prognosis. With this purpose, we suggest putting together all diagnosed dental resorptions into one of these four...

Invasive cervical resorption is a relatively uncommon form of external root resorption. It is characterized by invasion of cervical region of the root by fibrovascular tissue derived from the periodontal ligament. This case presents an invasive cervical resorption occurring in maxillary lateral incisor, following damage in cervical cementum from avulsion and intracoronal bleaching procedure. Fl...

Cellular mechanisms accounting for the osteolysis of rheumatoid erosions are poorly understood. Cells were isolated and characterised from the synovium of 16 patients with rheumatoid arthritis (RA) and four patients with osteoarthritis and their ability to resorb bone was assessed using a scanning electron microscope bone resorption assay. Macrophages were the major cell type isolated from the ...