OBJECTIVE The link between plasma resistin and obesity-related cardiometabolic disorders in children remains debatable. This study assessed the relationships of plasma resistin with cardiovascular risk factors, pro-inflammatory markers and insulin resistance index (HOMA-IR) in obese (Ob) adolescents and obese adolescents with metabolic syndrome (Ob-MS) compared to healthy controls (CO). METHO...

BACKGROUND The objective of this study was to conduct a systematic review of literature evaluating human resistin expression as a diagnostic factor in osteoarthritis development and to quantify the overall diagnostic effect. METHOD Relevant studies were identified and evaluated for quality through multiple search strategies. Studies analyzing resistin expression in the development of OA were ...

UNLABELLED Aim: Resistin plays a role in the pathogenesis of coronary artery disease and is related to mortality and morbidity through a number of mechanisms. We hypothesize that plasma resistin levels are increased in the presence of ischemia, as measured by GATED single- photon emission computed tomography myocardial perfusion scintigraphy (SPECT MPS), in comparison with nonischemic subjects....

AIMS Resistin is an adipocyte-derived factor implicated in obesity-associated type 2 diabetes (T2DM). This study examines the association between human serum resistin, T2DM and coronary heart disease. METHODS One hundred and fourteen Saudi Arabian patients (male: female ratio 46:68; age 51.4 (mean +/- SD)11.7 years; median and range: 45.59 (11.7) years and BMI: 27.1 (mean +/- SD) 8.1 Kgm2 med...

Plasma levels of the adipocyte product adiponectin, a putative insulin-sensitizing agent, are reduced in obesity, whereas plasma levels of resistin, an agent that some believe to confer insulin resistance, are thought to increase with obesity. Because adrenalectomy can increase insulin sensitivity, we hypothesized that adrenalectomy would increase expression of adiponectin and decrease expressi...

Introduction: Resistin, a complex multimeric structure which is secreted by adipose tissue and circulates in the blood, acts on the hypothalamus to increase sympathetic nerve activity, inhibit appetite and is associated with obesity, insulin resistance and cardiovascular disorders. In this study, we survey the cardiovascular effects of direct injection of resistin into specific cell group of th...

The prevalence of type 2 diabetes has been increased in Thais. Resistin is an adipokine that involve in glucose homeostasis and is a candidate gene for type 2 diabetes. We performed a case-control study in representative sample of 200 Thai volunteers, 105 controls and 95 type 2 diabetes subjects. The purposes of the present study were to investigate the association between two SNPs (single nucl...

Resistin and visfatin have been proposed as playing a role in the pathogenesis of insulin resistance. We assessed the relationship between their serum concentrations and insulin resistance in lean, obese diabetic and obese non-diabetic. We explore their relationship with inflammatory markers and anthropometric parameters in obese patients. We measured serum resistin, visfatin levels in obese di...

R esistin is a cysteine-rich protein that was discovered in 2001 and was initially proposed as a potential link between obesity and type 2 diabetes.1 Sources of resistin differ across species. In rodents, resistin is mainly located and secreted from adipocytes. However, in humans resistin is expressed primarily by macrophages, both inside and outside adipose tissue, and seems to be involved in ...