objective: the transdiagnostic cognitive behavioral treatments for treating the coexistence of anxiety and mood disorders received useful empirical supports in the recent years. however, these treatments still have moderate efficacy. following the improvements and developments in transdiagnostic protocols and considering the importance of repetitive negative thinking as a core transdiagnostic f...

transcranial magnetic stimulation (tms) has been applied to a growing number of psychiatric disorders as a neurophysiological probe, a primary brain-mapping tool and a candidate treatment. although most investigations have focused on the treatment of major depression, increasing attention has been paid to anxiety disorders. the aim of this study is to long time (for 30 days) effect of repetitiv...

Time evolving networks tend to have an element of regularity. This regularity is characterized by existence repetitive patterns in the data sequences graph metrics. As per our research, relevance such regular network has not been adequately explored. Such certain are indicative properties like popularity, activeness etc. which vital significance for any network. These closely indicated metrics ...

introduction: work-related musculoskeleta ldisorders (wmsds) of upperlimbs (ul)in the last 35 years have become extremely widespread, reaching epidemiclevels, inalladv ancedindustrializedcountries. they are considered the main cause of disability, time off work, and requests for healthcare . method and materials: for detailed risk assessment, iso -11228-3 is the preferred method. it is recommen...

DNA in situ hybridization (DNA ISH) is a commonly used method for mapping sequences to specific chromosome regions. This approach is particularly effective at mapping highly repetitive sequences to heterochromatic regions, where computational approaches face prohibitive challenges. Here we describe a streamlined protocol for DNA ISH that circumvents formamide washes that are standard steps in o...

Constitutive heterochromatin comprises a substantial fraction of the eukaryotic genomes and is mainly composed of tandemly arrayed satellite DNAs (satDNA). These repetitive sequences represent a very dynamic and fast evolving component of genomes. In the present work we report the isolation of Cricetus cricetus (CCR, Cricetidae, Rodentia) centromeric repetitive sequences from chromosome 4 (CCR4...

PURPOSE Subcellular Ca2+ signaling patterns, such as Ca2+ waves, gradients, and oscillations, are an important aspect of cell regulation, but the molecular basis for these signaling patterns is not understood. Because Ca2+ release patterns differ among isoforms of the inositol 1,4,5-trisphosphate (InsP3) receptor, the relationship between the distribution of these isoforms and subcellular Ca2+ ...