DNA repair mechanisms are critical for maintaining the integrity of genomic DNA, and their loss is associated with cancer predisposition syndromes. Studies in Saccharomyces cerevisiae have played a central role in elucidating the highly conserved mechanisms that promote eukaryotic genome stability. This review will focus on repair mechanisms that involve excision of a single strand from duplex ...

Smc5/6 is a structural maintenance of chromosomes complex, related to the cohesin and condensin complexes. Recent studies implicate Smc5/6 as being essential for homologous recombination. Each gene is essential, but hypomorphic alleles are defective in the repair of a diverse array of lesions. A particular allele of smc6 (smc6-74) is suppressed by overexpression of Brc1, a six-BRCT domain prote...

In this paper authors have considered a system having three units A, B1 and B2. A is controlled by a controller and B1 and B2 are independent. Two repairmen are involved in repair of the system. One of the repairmen (the first) is the foreman (boss) and the other an assistant (apprentice). Whenever any unit fails, repair is undertaken by boss. If the boss is busy in repairing and at the same ti...

This research discusses the variations of repair strategies used by lecturers and students during online learning process. The aim study is to compare strategy in university classroom COVID-19 pandemic Indonesia, Algeria Iran. data are a series utterances classes, which were collected from video audio recordings three different sessions. collection was carried out using record note techniques. ...

abstract background: renal insufficiency is a potential complication after infrarenal abdominal aortic aneurysm repair and is a significant risk factor for postoperative mortality and morbidity. the aim of this study was to analyze the effect of this risk factor, before and during operation. methods: in this prospective study, between 2003 and 2006, 45 patients underwent repair of an infrarenal...

 Abstract Background: Renal insufficiency is a potential complication after infrarenal abdominal aortic aneurysm repair and is a significant risk factor for postoperative mortality and morbidity. The aim of this study was to analyze the effect of this risk factor, before and during operation. Methods: In this prospective study, between 2003 and 2006, 45 patients underwent repair of an infrarena...

Objective(s): Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair. Blastema, a population of undifferentiated cells, represents characteristics of pluripotent mesenchymal stem cells and has the potentials to be used in regenerative medicine. The aim of this study was to ...

Background:  Parts of the implants placed over the meniscus during meniscal repair can wear down the cartilage in the contact zones and cause chronic synovitis. Placing horizontal sutures under the meniscus may overcome this potential hazard. The purpose of this prospective study was to evaluate the midterm results of arthroscopic meniscal repair using submeniscally placed out-in horizontal sut...