BACKGROUND Recent advances in the treatment of immunoglobulin light chain amyloidosis (AL) have dramatically improved survival. Kidney transplantation (KTx) has become more common but the long-term outcomes remain unknown and it is the objective of this study. METHODS Nineteen patients with AL underwent living (n = 18) or deceased (n = 1) KTx at our institution from 1999 to 2008 (median age 5...

Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by over-activation and dysregulation of the alternative complement pathway. Its estimated prevalence is 1-2 per million. The disease is characterized by thrombotic microangiopathy, which causes anemia, thrombocytopenia, and acute renal failure. aHUS has more severe course compared to typical (infection-induced) HUS and i...

hypertension is a common complication of kidney transplantation with the prevalence of 80%. studies in adults have shown a high prevalence of hypertension (htn) in the first three months of transplantation while this rate is reduced to 50- 60% at the end of the first year. htn remains as a major risk factor for cardiovascular diseases, lower graft survival rates and poor function of transplante...

A total of 73,707 primary renal transplants reported to the USRDS between 1988 and 1997 were examined to investigate the cause-specific risk for patient death associated with anti-lymphocyte antibody induction therapy (ABI). Cox proportional hazard models were used to estimate the relative risk of the use of ABI and patient death. All Cox models were corrected for potential confounding variable...

Posttransplantation lymphoproliferative disorder (PTLD) is a life-threatening Epstein-Barr virus (EBV)-associated B-cell malignancy occurring in 1% to 2% of renal transplantation patients. Host- and PTLD-related factors determining the likelihood of tumor response following reduction of immune suppression (IS) and antiviral therapy remain largely unknown. Standard therapy for PTLD is not well e...

loss of hearing is a known problem in patients with chronic renal failure, occurring in 40-xo% of cases and being most often of the high frequency sensorineural type. we performed a study on 50 patients with this disease, including 20 who had undergone a successful kidney transplantation. our results show an 80% incidence of hearing loss in these patients and a chance of improvement in at least...

TOPIC: Transplantation TYPE: Medical Student/Resident Case Reports INTRODUCTION: While, we find ample evidence of transplant associated-TTP (TA-TTP) secondary to calcineurin inhibitors (CNIs) after renal and hematopoietic stem cell transplantation, TA-TTP in solid organ (SOT) due CNI use remains a rare entity [1]. A few cases thrombotic microangiopathy have been reported lung, heart recipients....

More than 30 years ago diabetic patients with endstage renal disease (ESRD) were considered as inappropriate candidates for a chronic dialysis programme because of a very high mortality rate and poor longterm survival w1x. In spite of this negative attitude against diabetics on dialysis, not only more and more diabetic patients have been accepted to chronic renal replacement therapy, but diabet...

Abstract Background and Aims Atypical haemolytic uremic syndrome (aHUS) is a clinical entity characterized by acute kidney injury, thrombocytopenia microangiopathic hemolytic anemia. There are several cases of AHUS in non-renal solid organ transplants described the literature, included lung transplant. Kidney patient survival compromised this complication because lack an effective treatment. Ec...

Abstract Background: Renal transplantation (RT) is the transplantation of a kidney into a patient with end-stage renal disease and has become the treatment of choice for most patients with end-stage renal disease. The knowledge of renal vascular variations is of a great importance for the surgeons who approach the kidneys from the retroperitoneal o...