BACKGROUND The renal vasoconstrictor response to renal nerve stimulation is greater in congestive heart failure (CHF) rats than in control rats. This study tested the hypothesis that the enhanced renal vasoconstrictor response to renal nerve stimulation in CHF is a result of an impairment in the low-pass filter function of the renal vasculature. METHODS AND RESULTS In response to conventional...

We have used recombinant human erythropoietin (r-HuEPO) in children with chronic renal failure. There was significant improvement in anemia and wellbeing, along with regression of left ventricular mass and no change in the rate of decline of renal function. It is safe and effective in the pre-dialysis as well as the hemodialysis period. Considering the benefits of r-HuEPO, transplantation i...

Studies were performed to define the mechanisms involved in the redistribution of renal cortical blood flow to inner cortical nephrons which occurs during hemorrhagic hypotension in the dog. The radioactive microsphere method was utilized to measure regional blood flow in the renal cortex. Renal nerve stimulation decreased renal blood flow 40% but had no effect on the fractional distribution of...

We compared the renal vascular responses to angiotensin converting enzyme inhibition and renin inhibition to assess the influence of angiotensin II (Ang II). We examined the renal and endocrine responses to the renin inhibitor enalkiren, to captopril, and to placebo in nine healthy and nine hypertensive men on a 10-mmol sodium diet. Ang II was infused to assess effects of the agents on renal an...

Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression.  In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD...

1. Renal blood flow is decreased by hypotension due to bleeding, and glomerular filtration rate is disproportionately decreased. After a first 40 minute stage of hypotension at about 60 mm. Hg infusion of blood with consequent restoration of the general blood volume and arterial pressure usually results in a return to normal of renal blood flow and function although renal blood flow subsequentl...

Cholesterol synthesis inhibitors and fibrates both exercise effects that could influence BP and renal function in hypertension. To test this issue, transit-time ultrasound flow probes, implanted optical fibers, and laser-Doppler flowmetry were used for measurements of total and regional renal blood flows in lovastatin (40 mg/kg body wt) and bezafibrate (50 mg/kg body wt) chronically treated deo...

A semi-analytical investigation has been carried out to analyze unsteady MHD second-grade flow under the Dual-Phase-Lag (DPL) heat and mass transfer model in a vertical microchannel filled with porous material. Diffusion thermo (Dufour) effects and homogenous chemical reaction are considered as well. The governing partial differential equations are solved by using the Laplace transform method w...

This paper presents a comprehensive and exclusive thermodynamic analysis of counter flow heat exchanger under various operating and geometrical conditions. Analysis system (ANSYS) workbench 14.0 has been used for computational analysis and comparison with previous literature has been carried out in view of variable temperature and mass flow rate of hot and cold fluids. An analytical and statist...

This article explores the heat and mass transfer behaviour of magnetohydrodynamic free convective flow past a permeable vertical rotating cone and a plate filled with gyrotactic microorganisms in the presence of nonlinear thermal radiation, thermo diffusion and diffusion thermo effects. We presented dual solutions for the flow over a rotating cone and a rotating flat plate cases. Similarity var...