OBJECTIVES This clinical trial is registered at ClinicalTrials.gov. (NCT02476981)This randomized, prospective double-blind study compared remifentanil with dexmedetomidine for monitored anaesthesia care during minimally invasive corrections of vertebral compression fractures (vertebroplasty or kyphoplasty). METHODS Patients > 65 years of age with American Society of Anesthesiologists (ASA) cl...

BACKGROUND Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits in clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact of intraoperative pupillometry monitoring on perioperative opioid consumption in major gynecologic surgery. METHODS After receiving ethics committee appro...

BACKGROUND Coughing is a side effect of opioids that is rarely studied. Here, we evaluated the incidence of remifentanil induced coughing during anesthesia induction in an attempt to identify its risk factors and to examine the preventive effects of lidocaine and salbutamol. METHODS A total of 237 patients scheduled to undergo general anesthesia were allocated randomly into three groups. Grou...

BACKGROUND A decrease in core body temperature caused by heat distribution depends on the anesthetic agent used. The purpose of this study is to investigate the effects of sevoflurane and propofol on core temperature during laparoscopic major abdominal surgery requiring pneumoperitoneum of more than 90 min. METHODS Fifty adult patients undergoing laparoscopic major abdominal surgery were rand...

PURPOSE During emergence from anesthesia for a craniotomy, maintenance of hemodynamic stability and prompt evaluation of neurological status is mandatory. The aim of this prospective, randomized, double-blind study was to compare the effects of dexmedetomidine and remifentanil on airway reflex and hemodynamic change in patients undergoing craniotomy. MATERIALS AND METHODS Seventy-four patient...

BACKGROUND Experimental and clinical studies showed that intraoperative infusion of remifentanil has been associated with postoperative hyperalgesia. Previous reports suggested that spinal N-methyl-D-aspartate (NMDA) receptors may contribute to the development and maintenance of opioid-induced hyperalgesia. In the present study, we used a rat model of postoperative pain to investigate the role ...

normal 0 false false false en-us x-none ar-sa background: in this randomized, double‑blinded study, we investigated the preemptive effects of propofol, remifentanil or ketamine on post‑operative pain scores and analgesic requirements in elective lower abdominal surgeries under general anesthesia during the first 24 h of post‑operative period. materials and methods: seventy five patients, ...

conclusions as an oral premedication, clonidine can reduce surgical blood loss in lumbar spine posterior fusion surgery, even at the same levels of mean arterial pressure (map) with the control group. its use can be studied in more complicated spine surgeries, such as scoliosis and spinal deformity surgeries. results there was no statistically significant difference between groups in age (p = 0...

Purpose: To evaluate the effectiveness of combined remifentanil/sevoflurane anesthesia on hemodynamic stability and postoperative recovery in paediatric tonsil surgery.
 Methods: In this prospective study, a total 102 patients who underwent surgery Taihe County People's Hospital between February 2021 April 2022 were recruited randomized at ratio 1:1 to receive either propofol alone (contro...

BACKGROUND The aim of this study was to investigate the independent effect of remifentanil on the approximate entropy (ApEn) in frontoparietal montages. The authors investigated which montages were relevant to assess the remifentanil effect on the electroencephalogram. Spectral edge frequency and the canonical univariate parameter were used as comparators. METHODS Twenty-eight healthy volunte...