In this paper, a newsboy model is developed under uniformly distributed lead-time and demand that is an appropriate assumption in obtaining optimal relief inventory of humanitarian disasters. It is noteworthy that limited historical data are in hand on relief operations. Hence, analytical and approximate solutions for optimal relief order quan­tity were derived. The effect of lead-time uncertai...

This report provides recommendations for use of a newly developed recombinant outer-surface protein A (rOspA) Lyme disease vaccine (LYMErix, SmithKline Beecham Pharmaceuticals) for persons aged 15-70 years in the United States. The purpose of these recommendations is to provide health-care providers, public health authorities, and the public with guidance regarding the risk for acquiring Lyme d...

Background: Sharing masked interim results by the Data Safety Monitoring Board (DSMB) with non-DSMB members is an important issue that can affect trial integrity. Our survey's objective is to collect evidence to understand how seemingly masked interim results or result extrapolations are interpreted and discuss whether these results should be shared at interim. Methods: Conducted a 6 scenario-q...

ACIP Childhood/Adolescent Immunization Work Group Iyabode Akinsanya-Beysolow, MD1 Renée Jenkins, MD2 H. Cody Meissner, MD3 1Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC 2Department of Pediatrics and Child Health, Howard University College of Medicine, Washington, D.C. 3Tufts Medical Center, Boston, Massachusetts Corresponding contributor: Iyabod...

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Vaccines are recommended for adults on the basis of their age, prior vaccinations, health conditions, lifestyle, occupation, and travel. Reasons for current low levels of vaccination coverage for adult vaccines are multifactorial and include limited awareness among the public about vaccines for adults and gaps in incorporation of regular assessments of vaccine needs and vaccination into routine...

Introduction PPDG conducts an annual cross-project document or review process. For 2004, the third year of the SciDAC collaboratory pilot, we present an extended version of the Science Impact note that was presented around the time of the SciDAC PI meeting in March 2004. This document does not include work in progress, or address the needs and issues of the project.

microstructural evolutions of twinning induced plasticity (twip) steel during tensile straining wereinvestigated by in situ sem observations. the results indicated that slip lines and mechanical twins aswell as surface relief were increased with increasing strain, resulting in a stepped surface. additionally,these deformation mechanisms could change the shape of each grain via shear and rotatio...