نتایج جستجو برای: relaxivity
تعداد نتایج: 880 فیلتر نتایج به سال:
Here we report a new, bench-top synthesis for iron/iron oxide core/shell nanoparticles via the thermal decomposition of Fe(η(5)-C(6)H(3)Me(4))(2). The iron/iron oxide core/shell nanoparticles are superparamagnetic at room temperature and show improved negative contrast in T(2)-weighted MR imaging compared to pure iron oxides nanoparticles, and have a transverse relaxivity (r(2)) of 332 mM(-1) s...
Background Early gadolinium enhancement (EGE) has been indicated as major CMR criterion for the diagnosis of myocarditis according to the Lake Louise consensus (LLC). However, the suggested threshold of 4.0 for Early enhancement ratio (EER) specifically refers to use of conventional Gd-chelates (gadopentetate dimeglumine). Our purpose was to evaluate performance of a high relaxivity contrast ag...
We have synthesized the first steroid hormone-MR contrast agent conjugate designed to track the cell signaling process upon binding to a gene switch system. The derivative has a high relaxivity and when tested in vitro is active as a progesterone antagonist (RU-486). By combining a transcriptional system and a noninvasive imaging technology, such as MRI, it would be a powerful tool to research ...
Monomeric and dimeric bifunctional chelates based on the AAZTA (6-amino-6-methylperhydro-1,4-diazepinetetraacetic acid) platform bearing arylamino and isothiocyanate groups for conjugation to biomolecules were synthesised. Both systems were used for the preparation of high relaxivity dendrimeric (PAMAM G1) and multimeric octa-Gd(III) complexes. These systems show enhanced relaxometric propertie...
Nuclear magnetic resonance logging is an important formation detection technique in the petroleum industry, which always used to detect pore structure and fluid identification. However, conventional nuclear characterization methods assume that medium are fast diffusion regime. In complex formations, non-fast regimes (intermediate slow diffusion) also present. previous paper [13], a new method f...
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