Topical administration of a 1% forskolin suspension significantly reduced intraocular pressure in cynomolgus monkey eyes. The fall in intraocular pressure was associated with a significant (P less than 0.01) decrease in aqueous humor flow measured by a fluorophotometric technique. No significant change was found in tonographic outflow facility or pupillary diameter. A loss of effect on intraocu...

Following application of 50 microliter of 2N hydrochloric acid to the rabbit cornea, the intraocular pressure rapidly increases and remains markedly elevated for up to 3 hr. The initial rapid increase in intraocular pressure appears to be the result of acid-induced shrinkage of the outer collagenous coats of the eye. The sustained rise in intraocular pressure is mediated in part by prostaglandi...

PURPOSE The purpose of this study was to evaluate the fluctuation of intraocular pressure measurements obtained by Goldmann applanation tonometry, dynamic contour tonometry, and corneal compensated non-contact tonometry during office hours in glaucoma and healthy participants. This study also aims at correlating the intraocular pressure fluctuations with fluctuations of corneal hysteresis, cent...

Purpose: To evaluate intraocular pressure (IOP) and anterior chamber depth (ACD) change after phacoemulsification with posterior chamber intraocular lens implantation Methods: In this quasi-experimental study, 84 patients with senile cataract were included. All patients had normal IOP. Patients with traumatic and complicated cataract, any history of uveitis, glaucoma, or other ocular disease or...

The intraocular pressure of 59 patients with retinal vein occlusion was studied. Central retinal vein occlusion (CVO) was diagnosed in 24 patients and branch retinal vein occlusion (BVO) was diagnosed in the rest. The intraocular pressure of a sex and age matched group of controls was also studied for comparison. The intraocular pressure in the CVO group were significantly different from those ...

The intraocular pressure lowering effect in 30 patients with raised intraocular pressure and open angles following a single application in a randomised double-masked fashion of four concentrations of D-timolol (0.25%, 0.5%, 1.0%, and 2.0%), 0.25% L-timolol, and placebo are presented. The percentage reduction in intraocular pressure after four hours following single-drop instillation range from ...

Treatment of glaucoma continues to be directed at lowering intraocular pressure to decrease the likelihood of disease progression. In the future intraocular pressure reduction might be augmented by other therapeutic approaches. Interest has been increasing in preventing progression of glaucomatous optic neuropathy using approaches based on the premise that glaucoma is a neurodegenerative diseas...

When Policy Topic is covered Canaloplasty may be considered medically necessary as a method to reduce intraocular pressure in patients with chronic primary open-angle glaucoma under the following conditions:  Medical therapy has failed to adequately control intraocular pressure, AND  The patient is not a candidate for any other intraocular pressure lowering procedure (e.g. trabeculectomy or g...

Background: Succinylcholine remain unsurpassed in providing ideal intubating conditions in the shortest time among all available neuromuscular blocking agents hence is advocated as the drug of choice for rapid sequence endotracheal intubation. Aim: Study compared the effects of succinylcholine and rocuronium bromide on intraocular pressure. Materials and methods: Study was done in 30 samples of...