To solve the problem of deposits formation in exhaust pipe a diesel engine SCR (selective catalytic reduction) system, CFD (computational fluid dynamics) model was established to research influence structural parameters on wall film from perspective optimizing flow field. The solid structure simplified modeling without considering fields inside converter. simulation conditions were obtained thr...

Although tubulointerstitial nephritis with IgG4+ plasma cell (PC) infiltration is a hallmark of IgG4-related kidney disease (IgG4-RKD), only a few studies are available about the minimum number of IgG4+ PC needed for diagnosis along with IgG4+/IgG+ PC ratio in the kidney. In addition, the significance of the deposition of IgG or complement as a reflection of humoral immunity involvement is stil...

According to the amyloid theory, the appearance of amyloid-β (Aβ) deposits represents a pivotal event in late onset Alzheimer's disease (LOAD). Physiologically, Aβ42 monomers are cleaned by capillary resorption, enzymatic catabolism, and cerebrospinal fluid (CSF) transport. Factors that promote the oligomerization of Aβ42 must be specified. In vitro, these monomers spontaneously form neurotoxic...

The age-related altered expression of neuron-related proteins as seen in other regions of the central nervous system is expected in the aging retina. Using immunohistochemical techniques, we characterized the distribution and aggregation of tau, βA4-amyloid, α-synuclein, and ubiquitin in human retina obtained from 19 enucleated eyes of patients aged 49 to 87 years and correlated the findings wi...

Postmortem study of proliferative glomerulonephritis associated with human systemic lumpus has previously shown that an antigen related to mammalian type C RNA viral core (p30) proteins is deposited in the renal glomerular lesions with human immunoglobulins in an immune-complex pattern. In the present work, human immunoglobulins were sequentially eluted from the lupus glomerular immune deposits...

Department of Psychiatry, University of Geneva School of Medicine, 2, ch Petit Bel-Air, 1225 Geneva, Switzerland Early clinic-pathological studies demonstrated that the two cardinal lesions associated with Alzheimer disease (AD), neurofibrillary tangles (NFT) and amyloid deposits, have a differential impact on cognition both at early and late stages of the neurodegenerative process. In contrast...

Beta amyloid (Aβ) deposits are seen in aged individuals in many of the mammalian species that possess the same Aβ amino acid sequence as humans. Conversely, neurofibrillary tangles (NFT), the other hallmark lesion of Alzheimer's disease (AD), are extremely rare in these animals. We detected Aβ deposits in the brains of Tsushima leopard cats (Prionailurus bengalensis euptilurus) that live exclus...

Nonglacial deposits Artificial fill (Holocene)—Mud, sand, and gravel of varying proportions, possibly including foreign debris such as concrete, logs, timbers, or brick. Used for highway roadbeds and other construction. Thickness generally greater than 2 m. Mapped where fill substantially obscures or has altered original geologic deposit. Beach deposits (Holocene)—Soft sand, silt, and mud depos...

A number of voluminous, fine-grained, friable deposits have been mapped on Mars. The modes of origin for these deposits are debated. The feasibility for an origin by volcanic airfall for the friable deposits is tested using a global circulation model to simulate the dispersal of pyroclasts from candidate source volcanoes near each deposit. It is concluded that the Medusae Fossae Formation and E...

Astrocytes are implicated in the neuropathology of Alzheimer’s disease (AD) by clustering with other activated inflammatory cells at the sites of amyloid beta (Aβ) deposits formed in the cortex and hippocampus. Astrocytes are known to contribute to the clearance of Aβ in the AD brain. Also, adult but not neonatal mouse astrocytes are able to clear Aβ deposits from the tissue sections of transge...