The P38 mitogen-activated protein kinase (MAPK) signal transduction pathway is widespread in organisms and plays important roles immune activities. infection mechanism of environmental gram-negative bacteria on crustaceans an scientific problem. In this study, the cDNA full-length sequence Portunus trituberculatus (PtP38) was cloned its structure analyzed by bioinformatics methods. To study fun...

abstract cancer is the leading cause of death worldwide. current anticancer drugs involve various toxic side effects; efforts are ongoing to develop new anticancer agents especially from the screening of natural compounds. present study investigated cytotoxic effects and mode of cell death induced by the caspian cobra venom in some human cancer cell lines. cytotoxic effects of snake venom toxin...

Apoptosis or programmed cell death is a standard physiological mechanism. It essential to control the number of cells, balance division and death, regulate immune system, eliminate pathogen-infected cells. entailed different investigation determine related biochemical reactions such as activated caspase, Reactive Oxygen Species (ROS), Lipid Peroxidation (LPO), Evaluation Glutathione Content (GS...

Objective(s): Breast cancer is a devastating disease related to women. The anticancer properties of 8-hydroxyquinoline (8HQ) and the increasing use of graphene oxide (GO), as a drug delivery system with anti-cancerous properties, led us to investigate the toxicity and apoptosis-induction capability of 8HQ-coated GO on breast cancer cells compared with normal breast cel...

The present study aimed to explore the therapeutic effects of carvacrol on ulcerative colitis (UC) inflammation model induced by DSS (dextran sulfate sodium) in rats. Forty rats were randomly divided into blank, model, low-, middle-, and high-dose groups. drank 4.5% for 5 consecutive days induce UC except blank group. Different concentrations either or purified water supplied intragastric admin...