In this issue of Neuron, Chen and colleagues combine structural MRI and a twin-study design to investigate the influence of genetics on human cortical regionalization. Their results resonate with findings from animal studies and certain human syndromes of developmental cortical malformation.

OBJECTIVE To examine whether basing regionalization on risk-adjusted mortality would lead to better population outcomes than basing regionalization on procedure volume. DATA SOURCE We used secondary data from the California State Inpatient Database obtained from the Healthcare Costs and Utilization Project. STUDY DESIGN A population-based retrospective cohort study of 243 thousand patients ...

Tetrapods possess up to five morphologically distinct vertebral series: cervical, thoracic, lumbar, sacral and caudal. The evolution of axial regionalization has been linked to derived Hox expression patterns during development and the demands of weight-bearing and walking on land. These evolutionary and functional explanations are supported by an absence of similar traits in fishes, living and...

Abstract This article explores the policing structures that emerged in noughties England and Wales to tackle economic crime, such as Action Fraud National Intelligence Bureau. reviews some of growing literature on these structures, in-particular, two reports by Her Majesty’s Inspectorate Constabulary, Fire Rescue Services a major investigation Police Foundation which provides critical review po...

In this paper, we consider spatial predator-prey models with diffusion and prey-taxis. We investigate necessary conditions for pattern formation using a variety of non-linear functional responses, linear and non-linear predator death terms, linear and non-linear prey-taxis sensitivities, and logistic growth or growth with an Allee effect for the prey. We identify combinations of the above non-l...

Many studies have investigated the volume–outcome relationship for medical and surgical care, in which outcomes improve as the number of procedures performed at a particular hospital increases [1–5]. This can be interpreted as the effect of improving outcomes by repetitively performing the same procedures [6]. A similar effect has been described, known as the volume– cost relationship, where th...

Information from an outcrop is used as an analogue of a natural heterogeneous aquifer in order to provide an exhaustive data set of hydraulic properties. Based on this data, two commonly used borehole based investigation methods are simulated numerically. For a scenario of sparse sampling of the aquifer, the process of regionalization of the borehole hydraulic conductivity values is simulated b...

Regionalization is to divide a set of spatial objects into a number of spatially contiguous regions while optimizing an objective function, which is usually a homogeneity (or etereogenity) measure of the derived regions. In this paper we propose a new regionalization method for spatial functional data by means of a Dynamic Clustering Algorithm. The method optimizes a criterion of spatial associ...