Pheochromocytomas and paragangiomas are a class of neuroendocrine tumors with a widely variable clinical presentation ranging from paroxysmal episodes of critically elevated blood pressure to no clinical symptoms. Genetic predisposition to pheochromocytomas is well documented. Initial workup entails biochemical evaluation of urine catecholamine metabolites, intravenous contrast enhanced anatomi...

Malignant pheochromocytoma is a neuroendocrine tumor that originates from chromaffin tissue. Although osseous metastases are common, metastatic dissemination to the spine rarely occurs.Five years after primary diagnosis of extra-adrenal, abdominal pheochromocytoma and laparoscopic extirpation, a 53-year old patient presented with recurrence of pheochromocytoma involving the spine, the pelvis, b...

Currently, the only reliable indicator of malignancy in pheochromocytoma is the presence of distant metastasis or extensive local invasion; predicting behavior of pheochromocytoma remains challenging. We aimed to correlate the behavior of pheochromocytoma with its expression of nm-23, cyclooxygenase (COX)-2, and galectin-3 (genes used to predict the course of some neoplastic diseases), evaluate...

pheochromocytoma is a rare disease. a retrospective study of the signs and clinical course of this disorder was performed by evaluating medical records. our fidings indicate that the prevalence of pheochromocytoma was equal in men and women, and most patients (56%) were in their second and third decades of life. in 10% of the cases, the disease was bilateral, and in 13% it was outside the adren...

Pheochromocytoma is a neoplasia of chromaffin cells that is very rare in children. Its signs and symptoms result from the release of catecholamines. We report the case of a child with pheochromocytoma of difficult clinical management, confirmed on the anatomicopathological study, and cured after surgical resection.

Pheochromocytoma of the urinary bladder is rare, presenting usually with hypertension, hematuria and syncopal attacks. Such cases have usually been managed with open or laparoscopic partial cystectomy. We present a case of bladder pheochromocytoma that had unusual presenting symptoms, a paraneoplastic manifestation and was successfully managed with robotic technique.

Pheochromocytomas are rare neuroendocrine tumours of chromaffin tissues. They are catecholamine secreting tumours which cause severe hypertension and other systemic disturbances. Of all the causes of childhood hypertension, pheochromocytoma constitutes less than 1%. We report the case of a 12 years old child who presented with hypertensive encephalopathy, confirmed histologically to be secondar...

The acute intraoperative hypertension and tachycardia caused by an undiagnosed pheochromocytoma is a rare event for the anesthesia provider. If treatment is not prompt and successful, permanent and possibly lethal complications can ensue. This article reports what the author believes to be the first case study in which clevidipine (Cleviprex) was successfully used to treat a suspected, and late...

BACKGROUND: This study investigated clinical features, management, and outcome of pheochromocytoma and paraganglioma in children and adults. METHODS: Data of 15 patients with histologically confirmed pheochromocytoma or paraganglioma from 2002 to 2010 obtained from the China Medical University Hospital database were retrospectively