نتایج جستجو برای: refractory

تعداد نتایج: 57765  

2013
Clara B. Ocampo Paola A. Caicedo Gloria Jaramillo Raul Ursic Bedoya Olga Baron Idalba M. Serrato Dawn M. Cooper Carl Lowenberger

Aedes aegypti is the principal vector of Dengue viruses worldwide. We identified field collected insects with differential susceptibility to Dengue-2 virus (DENv-2) and used isofemale selection to establish susceptible and refractory strains based on midgut infection barriers. Previous experiments had identified higher expression of apoptosis-related genes in the refractory strain. To identify ...

Journal: :Haematologica 2015
Anna M Aalbers Marry M van den Heuvel-Eibrink Irith Baumann Michael Dworzak Henrik Hasle Franco Locatelli Barbara De Moerloose Markus Schmugge Ester Mejstrikova Michaela Nováková Marco Zecca C Michel Zwaan Jeroen G Te Marvelde Anton W Langerak Jacques J M van Dongen Rob Pieters Charlotte M Niemeyer Vincent H J van der Velden

Refractory cytopenia of childhood is the most common type of childhood myelodysplastic syndrome. Because the majority of children with refractory cytopenia have a normal karyotype and a hypocellular bone marrow, differentiating refractory cytopenia from the immune-mediated bone marrow failure syndrome (very) severe aplastic anemia can be challenging. Flow cytometric immunophenotyping of bone ma...

Journal: :Open access Journal of Neurology & Neurosurgery 2017

Journal: :Middle East Current Psychiatry 2021

Abstract Background Epilepsy has significant effects on the behavior of most people who suffer it. In some cases, seizure activity itself is manifested as a brief change in that might appear unusual to casual observer. Evidence also suggests epilepsy can affect when seizures are not occurring. Descriptions inter-ictal with have long and controversial history. The study aims assess personality d...

2015
Amit Agarwal Shyamsunder Sabat Krishnamurthy Thamburaj Sangam Kanekar

BACKGROUND Febrile seizures are the most common seizure disorder in childhood, associated with a significant rise in body temperature. However, post-infectious refractory afebrile form of seizures in previously healthy children is being increasingly recognized in around the world, which evolves into a chronic refractory form of epilepsy. The term 'Febrile infection-related epilepsy syndrome' (F...

2016
Sreenivasa Rao Sudulagunta Mona Sepehrar Mahesh Babu Sodalagunta Aravinda Settikere Nataraju Shiva Kumar Bangalore Raja Deepak Sathyanarayana Siddharth Gummadi Hemanth Kumar Burra

Introduction: Myasthenia gravis (MG) is an antibody mediated autoimmune neuromuscular disorder characterized by fatigable muscle weakness. A proportion of myasthenia gravis patients are classified as refractory due to non responsiveness to conventional treatment. This retrospective study was done to evaluate clinical profile, epidemiological, laboratory, and features of patients with MG and mod...

Journal: :Circulation 2010
Santi Trimarchi Kim A Eagle Christoph A Nienaber Reed E Pyeritz Frederik H W Jonker Toru Suzuki Patrick T O'Gara Stuart J Hutchinson Vincenzo Rampoldi Viviana Grassi Eduardo Bossone Bart E Muhs Arturo Evangelista Thomas T Tsai Jim B Froehlich Jeanna V Cooper Dan Montgomery Gabriel Meinhardt Truls Myrmel Gilbert R Upchurch Thoralf M Sundt Eric M Isselbacher

BACKGROUND In patients with acute type B aortic dissection, presence of recurrent or refractory pain and/or refractory hypertension on medical therapy is sometimes used as an indication for invasive treatment. The International Registry of Acute Aortic Dissection (IRAD) was used to investigate the impact of refractory pain and/or refractory hypertension on the outcomes of acute type B aortic di...

Journal: :Haematologica 2012
Julien Broseus Lourdes Florensa Esther Zipperer Susanne Schnittger Luca Malcovati Steven Richebourg Eric Lippert Jaroslav Cermak Jyoti Evans Morgane Mounier José Maria Raya François Bailly Norbert Gattermann Torsten Haferlach Richard Garand Kaoutar Allou Carlos Besses Ulrich Germing Claudia Haferlach Erica Travaglino Elisa Luno Maria Angeles Pinan Leonor Arenillas Maria Rozman Maria Luz Perez Sirvent Bernardine Favre Julien Guy Esther Alonso Nuhri Ahwij Andrés Jerez Sylvie Hermouet Marc Maynadié Mario Cazzola François Girodon

BACKGROUND Refractory anemia with ring sideroblasts associated with marked thrombocytosis was proposed as a provisional entity in the 2001 World Health Organization classification of myeloid neoplasms and also in the 2008 version, but its existence as a single entity is contested. We wish to define the clinical features of this rare myelodysplastic/myeloproliferative neoplasm and to compare its...

2002
Ofelia L. Zegarra-Moro Lucy J. Schmidt Haojie Huang Donald J. Tindall

Prostate cancer cells depend on androgens and the androgen receptor (AR) for survival. However, after androgen ablation therapy, tumors relapse to an androgen-refractory state. To determine whether the androgen receptor is critical for proliferation of androgen-refractory prostate cancer cells, we disrupted the activity of the androgen receptor with an antibody and an AR mRNA hammerhead ribozym...

Journal: :Journal of clinical periodontology 2002
Sigmund S Socransky Claire Smith Anne D Haffajee

BACKGROUND/AIM The purpose of the present investigation was to examine subgingival microbial profiles associated with refractory periodontitis and to seek such profiles in periodontally healthy, periodontally well-maintained elder and untreated periodontitis subjects. METHODS 36 subjects were defined as refractory on the basis of further attachment loss after scaling and root planing, surgery...

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