zrp2o7 nanoparticles (nps) as an efficient catalyst have been used for the preparation of 1,6-diamino-2- oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via one-pot coupling of hyrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes under reflux conditions in ethanol. using this method we obtained low reaction times, easy isolation of the targeted molecules, e...

Background and objectives: Gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .Hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...

a facile one-pot method with good yield for the synthesis of 2,4-dichloroquinoline and some related new derivatives by condensation of the appropriate primary aromatic amine with malonic acid in presence of excess phosphorus oxychloride is described.

One of the Fabaceae family that has potential as medicinal plant is white Turi (Sesbania grandiflora (L.) Pers.).The purpose this study was to determine content secondary metabolites which can be extracted using a various extraction methods.The method used are digestion, percolation, reflux, soxhlet, infusion, and decoction extraction. The plants come from Mojosari, Mojokerto.The results initia...

OBJECTIVE To assess the importance of iliac venous outflow obstruction in limbs with and without concomitant deep or superficial reflux, we performed a retrospective analysis of data contemporaneously entered into a set time-stamped electronic medical records program. MATERIAL AND METHOD Four hundred forty-seven limbs underwent iliac vein stenting of chronic, nonmalignant obstruction when gre...

INTRODUCTION AND OBJECTIVE Multiple options exist for the surgical management of vesicoureteral reflux (VUR). We report on our 10-year experience using the inguinal approach to extravesical ureteral reimplantation (EVR). MATERIALS AND METHODS Patient characteristics of age, gender, and reflux grade were obtained and outcomes of operative time, hospital stay, and radiographic resolution were a...

Background/Aims Neurologically impaired patients frequently suffer from gastrointestinal tract problems, such as gastroesophageal reflux disease (GERD). In this study, we aimed to define the risk factors for GERD in neurologically impaired children. Methods From May 2006 to March 2014, 101 neurologically impaired children who received 24-hour esophageal pH monitoring at Severance Children's H...

OBJECTIVE To study the prevalence of signs and symptoms of reflux in snorers with suspected OSA. METHOD This cross-sectional study enrolled 74 patients assessed positive for OSA with the Berlin questionnaire. The subjects were followed up at the sleep disorder ward of a university center. Studied variables included the BMI, the Epworth sleepiness scale, the reflux symptom index (RSI), the ref...

The mechanical force relationships that distinguish normal from chronic reflux at sphincter opening are poorly understood and difficult to measure in vivo. Our aim was to apply physics-based computer simulations to determine mechanical pathogenesis of gastroesophageal reflux. A mathematical model of the gastroesophageal segment (GES) was developed, incorporating the primary anatomical and physi...

background and objectives: gastroesophageal reflux is a common chronic disease that impairs individuals’ quality of life, wherein patients should receive prolonged, and sometimes lifelong, treatment with chemical drugs, that in addition to high costs they can lead to side effects in the long term .hawthorn fruit is one of the drugs used in traditional medicine to relieve reflux symptoms and to ...