نتایج جستجو برای: reflow phenomenon

تعداد نتایج: 159457  

Journal: :Pakistan Armed Forces Medical Journal 2022

The no reflow phenomenon is a feared complication in Percutaneous Coronary Intervention (PCI) procedures including elective as well primary PCI (Percutaneous Intervention), and results worse prognosis. A number of etiological factors are involved pathogenesis phenomenon. These include distal athero embolization, ischemic reperfusion injury, microvascular spasm endothelial dysfunction. treatment...

Journal: :Heart 1999
J Trevelyan M Been

A 73 year old man was admitted with haematemesis and was found to have a pangastritis. Three days later he developed central chest pain, and ECG changes indicated an acute anterior myocardial infarction. In view of his recent haematemesis we performed emergency coronary angiography, which showed proximal occlusion of the left anterior descending (LAD) artery (TIMI 0 flow), with normal circumfle...

Journal: :Circulation 1992
G K Asimakis J B Zwischenberger K Inners-McBride L A Sordahl V R Conti

BACKGROUND Adenine nucleotides (AdNs) are lost from the mitochondrial fraction of the heart cell during ischemia. It is unknown whether this pool of AdNs can be replenished after reperfusion. The purpose of this study was to evaluate the postischemic recovery of the mitochondrial AdN pool. METHODS AND RESULTS The left anterior descending coronary artery (LAD) of the canine heart was occluded ...

Journal: :Circulation 2002
Jun-ichi Kotani Shinsuke Nanto Gary S Mintz Masafumi Kitakaze Tomoki Ohara Takakazu Morozumi Seiki Nagata Masatsugu Hori

BACKGROUND No-reflow associated with direct angioplasty (PCI) of patients with acute coronary syndromes (ACS) is associated with unfavorable results. METHODS AND RESULTS We used a new thrombectomy device to treat 51 lesions in 48 consecutive ACS patients (40 male and 8 female; mean age 63 years) and conducted a microscopic analysis of aspirates and blood samples retrieved from the culprit cor...

Journal: :American journal of physiology. Heart and circulatory physiology 2002
Thorsten Reffelmann Sharon L Hale Guohu Li Robert A Kloner

No reflow after acute myocardial infarction is an important predictor of infarct size and clinical outcome. However, the exact relationship between no reflow and infarct size remains to be determined, particularly because no reflow may progress during the time course of reperfusion. Control groups of five previous protocols using the anesthetized, open-chest rabbit model of coronary artery occl...

Journal: :American journal of physiology. Heart and circulatory physiology 2000
P Golino M Ragni P Cirillo A Scognamiglio A Ravera C Buono A Guarino O Piro C Lambiase F Botticella M Ezban M Condorelli M Chiariello

Oxygen free radicals induce de novo synthesis of tissue factor (TF), the initiator of the extrinsic pathway of coagulation, within the coronary vasculature during postischemic reperfusion. In the present study we wanted to assess whether TF expression might cause myocardial injury during postischemic reperfusion. Anesthetized rabbits underwent 30 min of coronary occlusion followed by 5.5 h of r...

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